نتایج جستجو برای: myelogenous leukemiablood cancer

تعداد نتایج: 915870  

Journal: :Haematologica 2015
Erwin M Lee Dean Yee Samantha J Busfield Julie F McManus Nik Cummings Gino Vairo Andrew Wei Hayley S Ramshaw Jason A Powell Angel F Lopez Ian D Lewis Martin N McCall Richard B Lock

The prognosis of older patients with acute myelogenous leukemia is generally poor. The interleukin-3 receptor α-chain (CD123) is highly expressed on the surface of acute leukemia cells compared with normal hematopoietic stem cells. CSL362 is a fully humanized, CD123-neutralizing monoclonal antibody containing a modified Fc structure, which enhances human natural killer cell antibody-dependent c...

Journal: :Journal of the National Comprehensive Cancer Network 2009

Journal: :Cancer research 1981
N T Bech-Hansen B M Sell J J Mulvihill M C Paterson

The gamma-ray sensitivity of skin fibroblasts from six members of a cancer family was investigated using a colony-forming assay. Fibroblasts from the three members with cancer (two sisters with acute myelogenous leukemia and the mother with cervical carcinoma) showed a significant (p less than 0.05) increase in radiosensitivity, while three members without cancer (the father and two sons) showe...

Journal: :Baylor University Medical Center Proceedings 2008

Journal: :Hamatologie und Bluttransfusion 1976
P S Sarin R C Gallo

High levels of terminal deoxynucleotidyl transferase have been observed in leukocytes of 7 out of 20 patients with chronic myelogenous leukemia in acute blast phase of the disease. These levels are comparable to the levels observed in human and calf thymus gland and cell lines with some T cell characteristics (Molt 4 and 8402). Negligible levels of this activity were observed in chronic myeloge...

Journal: :Cancer research 1973
C Sauter U Baumberger S Ekenbark J Lindenmann

Replication of a strain of fowl plague virus adapted to human myeloblasts was studied in leukemia cell cultures derived from the venous blood of 20 adult patients suffering from acute leukemia (15 acute myelogenous, 4 acute lymphatic, and 1 chronic myelogenous leukemia in acute blastic crisis). Virus multiplication was observed in the cultures of 18 patients. Sufficient adaptation of the virus ...

Journal: :British Journal of Haematology 2000

2004
N. Torben Bech-Hansen Brenda M. Sell John J. Mulvihill Malcolm C. Paterson

The y-ray sensitivity of skin fibroblasts from six members of a cancer family was investigated using a colony-forming assay. Fibroblasts from the three members with cancer (two sisters with acute myelogenous leukemia and the mother with cervical carcinoma) showed a significant (p < 0.05) increase in radiosensitivity, while three members without cancer (the father and two sons) showed a normal r...

Journal: :Phytomedicine : international journal of phytotherapy and phytopharmacology 2003
C Bézivin S Tomasi F Lohézic-Le Dévéhat J Boustie

Eight lichens were extracted successively with n-hexane, diethyl ether and methanol using a Soxhlet process. The cytotoxic activity of the 24 lichen extracts was evaluated in vitro using two murine (the L1210: lymphocytic leukaemia, and the 3LL: Lewis lung carcinoma) and four human (the K-562: chronic myelogenous leukaemia, the U251: glioblastoma, the DU145: prostate carcinoma, and the MCF7: br...

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