نتایج جستجو برای: mutation detection method

تعداد نتایج: 2333870  

Journal: :The Ulster Medical Journal 1997
Patrick J Morrison

Since the original description of Helicobacter plvori by Warren and Marshall in 1983 there has been a virtual explosion in interest in this organism. It is now causally linked to chronic gastritis, peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma and possibly gastric cancer. It has proved to be the single most important advance in modern gastroenterology. This book is a ...

Journal: :journal of physical & theoretical chemistry 2008
s. irani m. monajjemi s.m atyabi m. sadegizadeh m. heshmat

p53 is one of the gene that has important role in human cell cycle and in the human cancers too.models of codon substitution make it possible to separate mutational biases in the dna fromselective constraints on the protein, and offer a great advantage over amino acid models forunderstanding the evolutionary process of proteins and protein-coding dna sequences. in thiswork, we investigated abou...

Helicobacter Pylori (H. pylori) as a gram-negative bacterium is the most common infection of the gastrointestinal tract, and worldwide it affects the children over three years of age. H. pylori could cause gastrointestinal and extra-intestinal manifestations. Antibiotic resistance can happen primarily and occurs during treatment. We aimed to evaluate the resistance gene of H. pylori obtained fr...

Journal: :middle east journal of cancer 0
hind dehbi genetics and molecular pathology laboratory, medical school of casablanca, hassan ii university, casablanca, morocco yaya kassogue genetics and molecular pathology laboratory, medical school of casablanca, hassan ii university, casablanca, morocco sanaa nasserddine genetics and molecular pathology laboratory, medical school of casablanca, hassan ii university, casablanca, morocco asma quessar department of onco-hematology, ibn rochd university hospital, casablanca, morocco sellama nadifi genetics and molecular pathology laboratory, medical school of casablanca, hassan ii university, casablanca, morocco

background :according to numerous studies, fms-like tyrosine kinase 3, internal tandem duplication, and the d835 mutation are associated with a poor prognostic clinical outcome in acute myeloid leukemia patients. detection of the fms-like tyrosine kinase 3 mutation in patients who present with normal karyotype acute myeloid leukemia helps in both the understanding of the disease and the treatme...

2011

addressed the feasibility of obtaining sensitive, accurate, and reproducible mutation detection results in synthetic templates, cell lines, and FFPE tissue samples using TaqMan Mutation Detection Assays. Analytical performance assessed with synthetic templates and genomic DNA (gDNA) extracted from cell lines or model FFPE cell lines indicates that TaqMan Mutation Detection Assays have a minimum...

Journal: :iranian journal of allergy, asthma and immunology 0
"anna isaian mostafa moin zahra pourpak nima rezaei asghar aghamohammadi masoud movahedi

primary immunodeficiency disorders are a heterogeneous group of genetic disorders, with different modes of inheritance, consisting of more than 100 different types. we constructed the dna banking of primary immunodeficiency disorders for the first time in iran. the dna of 31 immunodeficient patients and their families (total of 92 samples) were collected, as the first step for construction of d...

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