نتایج جستجو برای: mutagenicity ames
تعداد نتایج: 6490 فیلتر نتایج به سال:
Although products of pyrolysis are often cytotoxic and mutagenic, the relationship between the type of material pyrolysed and the toxicity of the resulting pyrolysis products is poorly understood. The objective of this study was to evaluate and compare the cytotoxicity and mutagenicity of several types of common pyrolysis products. The cytotoxicity and mutagenicity of these products were assess...
Traditional Chinese Medicines (TCM) are histidine-containing biological samples, they are commonly orally taken in the form of water extracts. False-positive results of TCMs’ water extracts may get when using standard Ames test, therefore the interference resulted from histidine within the samples must be eliminated or reduced, and the standard Ames test needs to be modified. This mini-review s...
Pesticides widely used in the agricultural market led to an increase quality and yield of crops. However, pesticides are a major concern environment as they also harm non-target creatures, because pesticide resistance, mutagenic carcinogenic effects. In this study, we aimed research potential mutagenicity Karate Zeon which is synthetic pyrethroid insecticide. Salmonella typhimurium assay (Ames ...
Most herbal medicines utilized in complementary and alternative medicine lack safety evaluation setting our lives under unwarranted risks. Present study comprised of genotoxic and cytotoxic appraisal of Terminalia citrina fruits which are used as a folklore medicine for treatment of various ailments. Aqueous and ethanolic extracts of T. citrina fruit extracts were evaluated for the presence of ...
The investigation of the link between diet and cancer in man has resulted in the identification of a variety of carcinogenic and mutagenic principles in food, particularly cooked meat (Furihata & Matsushima, 1986), the most mutagenic of these compounds being the amino-imidazoaza-arenes:2amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), 2amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (DiMeIQx...
Postmitochondrial supernatant from rat liver and kidney homogenates transformed cysteine into a mutagen that reverted bacteria of the strain Salmonella typhimurium TA100 to histidine independence. Glutathione was also activated by kidney postmitochondrial supernatant but not by liver preparations. Hence, important endogenous compounds of mammals are positive in the most commonly used short-term...
Driven by new regulations and animal welfare, the need to develop in silico models has increased recently as alternative approaches to safety assessment of chemicals without animal testing. This paper describes a novel machine learning ensemble approach to building an in silico model for the prediction of the Ames test mutagenicity, one of a battery of the most commonly used experimental in vit...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید