CONTEXT The term growing pains describes a common, benign syndrome of recurrent discomfort that occurs in young children. First described in the 1800s, the etiology of this condition remains unclear. The peak incidence does not correspond to a time of rapid growth. Children typically report bilateral pain in the lower extremities that occurs late in the day or at night. EVIDENCE ACQUISITION T...

1Department of Cognitive Neuroscience, Institute for Cognitive Science Studies, Tehran, Iran 2Department of Dental Anatomy, Faculty of Dentistry, Islamic Azad University, Tehran, Iran 3Programme in Experimental Medicine and Therapy, Doctoral School in Life and Health Sciences, Maxillofacial Surgery Section, Surgical Sciences Department, S. Giovanni Battista Hospital, University of Turin, Turin,...

Background: MeCP2, methyl-CpG-binding protein 2, binds to methylated cytosines at CpG dinucleotides, as well as to unmethylated DNA, and affects chromatin condensation. MECP2 mutations in females lead to Rett syndrome, a neurological disorder characterized by developmental stagnation and regression, loss of purposeful hand movements and speech, stereotypic hand movements, deceleration of brain ...

Chronic musculoskeletal pains are multifaceted, and Central sensitization is a potential pathophysiological mechanism underlying group of chronic pain disorders. Neurophysiology education knowledge patient satisfaction levels subjects may contribute to central nervous system sensitization. Hence, the aim study was evaluate impact neurophysiology on in large population with pain. The included 20...

Cogan's syndrome (CS) is a chronic inflammatory disorder of unknown etiology that most commonly affects young adults. Clinical hallmarks are bilateral interstitial keratitis and vestibuloauditory dysfunction. Association between CS and systemic vasculitis as well as aortitis also exists. The diagnosis of CS is based upon presence of characteristic inflammatory eye disease and vestibuloauditory ...

An ergonomics assessment was conducted in a modern, automated hospital-based laundry to investigate workers' complaints of musculoskeletal aches and pains and general fatigue. Numerous job stressors were identified requiring ergonomic solutions, including prolonged standing, excessive manual handling of transport units, non-adjustability of workstations, work pacing, awkward postures, lack of j...

Tamoxifen in treatment of breast cancer is replaced by aromatase inhibitors (AI’s) which blocks and prevent estrogens by inhibiting aromatase enzyme. Treatments in breast cancer, such as oophorectomy, gonadotropin-releasing hormone (GnRH) agonists, chemotherapy and AIs, all decrease endogenous estrogens and cause significant decrease in bone mineral density (BMD) leading to bone loss and increa...

Erythema ab igne (EAI) is a reticulated, telangiectatic, and hyperpigmented skin eruption resulting from chronic exposure to long-term moderate heat. The incidence has decreased substantially today because of the advent of modern central heating systems. Recently, we encountered a patient who developed EAI after 2 weeks of footbaths with Chinese herbal remedies, which she used to treat her acut...

Construction is a heavy manual industry where working into later life can be a challenge. An interview study was conducted to explore workers' understanding of their health at work and ways of making their jobs easier, safer or more comfortable. Using purposive sampling, 80 trades' workers were selected from construction sites in the UK. The Nordic Musculoskeletal Questionnaire and Work Ability...