Introduction Sequential MR examinations of the brain are the primary method for clinical as well as research assessment of the effects of therapy on brain tumors. In clinical practice, visual comparison is the primary method of assessing changes that indicate tumor response or progression. This is a labor-intensive process involving visual search for changes between examinations on multiple ima...

MNTI is a rare tumor of indeterminate histogenesis and molecular signature. We performed methylation copy number variation (CNV) profiles in patients with (n = 7) PAT 1) compared to the brain classifier v11b4 (BT-C) medulloblastoma (MB) group 3/4 v1.0 (MB3/4-C). The patients’ mean age was 8 months (range: 4–48). BT-C classified five MNTIs one (relapse) as class family MB-G3/G4, subclass 3 (scor...

PURPOSE To describe the imaging and pathologic findings of malignant rhabdoid tumor (MRT), a rare primary brain neoplasm affecting children. METHODS The CT and/or MR features, pathologic findings, and clinical records of three children with primary MRT of the brain were retrospectively reviewed. RESULTS The tumors, large, left-sided cerebral masses, were intraventricular in two cases. MR im...

INTRODUCTION Malignant primary brain tumors are one of the most aggressive cancers. Pretreatment serum nonneuronal biomarkers closely associated with postoperative outcomes are of high clinical relevance. The present study aimed to identify potential pretreatment serum biomarkers that may influence oncological outcomes in patients with primary brain tumors. METHODS A total of 74 patients unde...

conclusion statistical analysis of susceptibilities of ms patients versus healthy subjects found no excess deposition of calcium content in deep gray matter of ms patients. calcification may not be considered as a biomarker of prognosis in ms. results magnetic susceptibility(x) of calcium content was assessed by number of pixels induced by gp and put in ms patients as well as healthy subjects. ...

the brain is a rare site for metastasis in most extracranial pediatric solid tumors, including wilm’s tumor. outcome for these patients are generally dismal. very few cases have been reported to have good survival even after therapy. this paper reports a case of stage iv wilm’s tumor with lung metastases in a patient who developed a solitary brain metastasis five months after completion of chem...

Introduction: Glioma is the most common type of primary brain tumor that originates from glial tissues. These types of tumors have a high degree of malignancy and poor prognosis and low survival rates. The evaluation response to treatment is essential to decide whether present treatment is adequate or need for alternative therapy. The aim of this study was to evaluate the resp...

There are over 120 types of brain tumor and approximately 45% of primary brain tumors are gliomas, of which glioblastoma multiforme (GBM) is the most common and aggressive with a median survival rate of 14 months. Despite progress in our knowledge, current therapies are unable to effectively combat primary brain tumors and patient survival remains poor. Tumor metabolism is important to consider...