Covalent amphiphilic polyoxometalates generated from alkylphosphonic acids have been synthesized, characterized and monitored by multinuclear NMR spectroscopy. Among them, K3H[γ-SiW10O36(C12H25PO)2] has been successfully used as a surfactant for the stabilization of a Winsor I type microemulsion system.

cis-[(Cy3P)2Pt{B(OMe)2}2] (1) was obtained in quantitative yield and fully characterised. The thermal stability of 1 was investigated in solution using multinuclear NMR spectroscopy revealing a hitherto unknown temperature-dependent equilibrium between 1 and the corresponding starting materials [Pt(PCy3)2] and free B2(OMe)4.

Osteoclasts are bone-resorbing multinuclear cells derived from hematopoietic stem cells or monocyte/ macrophage lineage cells. Recent identification of RANK/RANKL has provided new insights into the osteoclast differentiation pathway, enabling us to generate osteoclasts without stromal cells, which support osteoclastogenesis. In order to establish a pure osteoclast culture system, we identified ...

Uneven blastomere cleavage in human embryos of 'good morphology', i.e. those normally used for transfer, is a phenomenon which has been poorly investigated. The main objective in this study was to probe deeper into the aetiology behind previous findings that embryos with uneven cell cleavage have a lower developmental capacity in comparison with evenly cleaved embryos. Our hypothesis was that u...

195Pt and 1H NMR has been used to show that addition of chlorine and bromine to [Pt(CN)4]2_ in presence of perchloric acid in water results in cyanide and water scrambling with formation of eleven complexes of the type [Pt(CN)4-nCl(H2O)n+1](n-1)+ (n=0, 1, 2, 3, 4). Addition of NBu4OH ...

Free radical polymerization of B-vinyl- and B-styryl-functionalized azaborinine monomers gives well-defined hybrid polymers that were fully characterized by multinuclear NMR and GPC analysis; their solubility, thermal characteristics, and photophysical properties are dramatically different from those of the all-carbon polystyrene analogues.

School of Chemistry and Trinity Biomedica Dublin, The University of Dublin, Dublin [email protected] School of Chemistry and Centre for Res Nanodevices (CRANN), Trinity College Dub Ireland Chemistry, Faculty of Natural and E Southampton-Higheld, Southampton, SO17 † Electronic supplementary informat (multinuclear NMR, IR HRMS) charact powder diffraction and uorescen 10.1039/c6sc04367d Cite this:...

We describe the use of the semi-empirical molecular orbital method PM3 (parametric method 3) to study the electronic structure of iron-sulphur proteins. We first develop appropriate parameters to describe models of the redox site of rubredoxins, followed by some preliminary calculations of multinuclear iron systems of relevance to hydrogenases.

Identification of receptor activator of nuclear factor-kappaB (RANK) and RANK-ligand (RANKL) has provided new insights into the osteoclast differentiation pathway. Osteoclast precursor cells were isolated using monoclonal antibodies against c-Fms and RANK, and the effect of adherence on the in vitro differentiation and proliferation of these cells was examined in 2 different types of stromal-ce...