Background: Collagenous colitis is characterised by diarrhoea, lymphocytic inflammation, and a thickened subepithelial collagen layer in the colorectal mucosa. No standard treatment of the disease is established. Aims: To investigate the clinical and histological effect of oral budesonide (Entocort, AstraZeneca) in the treatment of collagenous colitis. Patients: Twenty patients with collagenous...

Five specimens of Arapaima gigas caught in the Araguaia River (State of Mato Grosso, Brazil) were investigated for helminths in 2004. Numerous adult specimens of the rhapidascarid nematode Goezia spinulosa were found in stomach ulcers in all the specimens of A. gigas and were surrounded by thickening of the mucosa. The gastric glands of all the fish were necrotic and there was a severe and diff...

Periodontitis are infections that may cause systemic consequences. Due to that it is important to make an accurate histopathologic diagnosis as soon as possible. The aim of this study was to determine the main changes from the gingival mucosa biopsy taken from generalized chronic periodontitis (GCP) patients by light microscopy (LM) and transmission electron microscopy (TEM). The results were c...

Mucus is secreted throughout the gastro-intestinal tract by a variety of specialised cells located in glands or in the surface epithelium. The prime func­ tion of the mucus layer is to protect the delicate underlying mucosa from dam­ age by potentially harmful agents in the lumen (such as digestive enzymes and bacteria) and by the mechanical forces associated with digestion and the pas­ sage of...

Definition Human Papillomaviruses (HPVs) are a group of DNA viruses, which have a remarkable target cell specificity: they have been reported principally in anogenital tract, urethra, skin, larynx, tracheobronchial mucosa and oral cavity. More than 100 different types of HPV have been classified and they are divided into high (e.g. 16,18, 31) and low oncogenic risk genotypes (e.g. 11, 42, 36), ...

Heterotopic gastrointestinal cysts are rarely found in the oral cavity. Most of these cysts are lined with gastric mucosa and involve the tongue. There have been no reported heterotopic intestinal cysts of the submandibular gland that are completely lined with colonic mucosa. An 8-year-old girl presented with an enlarging swelling in the left submandibular area, and a 4-cm unilocular cyst was f...

BACKGROUND The effectiveness of photodynamic therapy (PDT) for ablation of high grade dysplasia (HGD) in Barrett's esophagus (BE) is typically reported histologically. Following successful PDT, Barrett's mucosa is replaced with neosquamous mucosa. The objective of this study was to compare the expression of p53 protein in neosquamous mucosa as compared to that in HGD samples not treated with PD...

E4 CUTIS WWW.CUTIS.COM To the Editor: A 34-year-old woman presented for evaluation of dry mouth and painless peeling of the oral mucosa of 2 months’ duration. She denied any other skin eruptions, dry eyes, vulvar or vaginal pain, or recent hair loss. A recent antinuclear antibodies test was negative. The patient’s medical history was otherwise unremarkable and her current medications included m...

Tissue engineering of bone and oral mucosa have been extensively studied independently. The aim of this study was to develop and investigate a novel combination of bone and oral mucosa in a single 3D in vitro composite tissue mimicking the natural structure of alveolar bone with an overlying oral mucosa. Rat osteosarcoma (ROS) cells were seeded into a hydroxyapatite/tri-calcium phosphate scaffo...

Angina bullosa hemorrhagica is a rare and benign disorder, usually localized in the subepithelial layer of the oral, pharyngeal and esophageal mucosa. The lesions are characterized by their sudden onset. They appear as a painless, tense, dark red and blood-filled blister in the mouth that rapidly expand and rupture spontaneously in 24-48 hours. The underlying etiopathology remains ill defined, ...