Sir, Follicular mucinosis (FM) is a non-speci¢c histological reaction pattern characterized by mucinous degeneration of the outer sheath of follicles and sebaceous glands, accompanied by a variable in£ammatory cell in¢ltrate (1). The clinical expression is extremely variable. It may occur as a primary disorder or associated with benign or malignant diseases (2 ^ 4). We describe a patient who de...

A case of exuberant pretibial mucinosis in a patient with normal thyroid function is reported. A review of literature on possible etiologies other than thyroid disease for the accumulation of mucin in the pretibial area is presented. In the patient described, it is possible that vascular insufficiency is involved. However, this is not the only factor responsible for the accumulation of mucin, s...

BACKGROUND Scleromyxoedema is a variant of papular mucinosis affecting the skin and internal organs. The different therapeutic approaches proposed for scleromyxoedema are still unsatisfactory. Intravenous immunoglobulin (IVIg) has been successfully employed in the treatment of connective tissue diseases and vasculitides. PATIENTS The successful treatment of three cases of scleromyxoedema with...

Cutaneous focal mucinosis (CFM) is a localized form of cutaneous dermal mucinosis clinically presenting as an asymptomatic skin-colored papule or nodule. The etiopathogenesis of CFM is unclear, but it is thought to represent a reactive lesion. Although trauma has been suspected as a triggering factor, it has never been proven in cases of CFM. We report 2 male patients with trauma-induced CFM ar...

Scleromyxedema is an idiopathic cutaneous mucinosis characterized by a papular eruption, skin induration and paraproteinemia. Histologically, fibrolast proliferation can be observed in the upper dermis associated with a mucine deposition. Treatment is difficult and at present there is no totally effective therapeutic modality to control the disease. The present report is on a 68-year-old patien...