Myxopapillary ependymoma (MPE) is a World Health Organization grade I ependymoma that is quite rare and generally thought to be benign. Possible drop metastasis from MPE has been reported three times in the literature; in each case there were cotemporaneous additional MPE lesions. We report the case of a man who had a piecemeal gross total resection of a MPE at L1-L3 followed by adjuvant extern...

The aim of the study was to study the PK of AST2818 tablets after one oral dose in healthymale subjects on an empty stomach and in a postprandial state and to evaluate the effect of food onAST2818 bioavailability. Sixteen healthy Chinese male subjects were randomly divided into twogroups: a fasting-postprandial group and a postprandial-fasting group. T...

Introduction: There are problems in the differential diagnosis of malignant pleural effusion (MPE) and parapneumonic effusion (PPE). We investigated the diagnostic value of levels of carcinoembryonic antigen (CEA) and C-reactive protein (CRP) in the discrimination of MPE and PPE. Materials and Methods: Twenty-eight patients with MPE and 21 patients with PPE were assessed. CEA and CRP levels wer...

BACKGROUND Malignant pleural effusion (MPE) can occur during the progression of various cancers. However, factors, such as the incidence of MPE associated with different types of cancers and its potential for diagnosing previously undetected cancers, are unknown. Moreover, MPE may accompany potentially curable cancers or those with a favorable survival prognosis with adequate treatment. The pre...

The isocyclic ring of bacteriochlorophyll (BChl) is formed by the conversion of Mg-protoporphyrin monomethyl ester (MPE) to protochlorophyllide (PChlide). Similarities revealed by blast searches with the putative anaerobic MPE-cyclase BchE suggested to us that this protein also uses a cobalamin cofactor. We found that vitamin B(12) (B(12))-requiring mutants of the bluE and bluB genes of Rhodoba...

BACKGROUND VEGF is critical in the pathogenesis of malignant pleural effusion (MPE). To understand the clinical benefits of antiangiogenic agents, the efficacy of chemotherapy containing bevacizmab was investigated in patients with lung adenocarcinoma-induced MPE. METHODS The data of lung adenocarcinoma patients with MPE treated with bevacizumab plus chemotherapy on day 1, every three weeks, ...

purpose: to report two patients with keratoconus who underwent regrafting to correct anisometropia and high astigmatism after penetrating keratoplasty. patients and findings: the first case is a 34-year-old man with keratoconus who had undergone penetrating keratoplasty. the sutures were removed 6 months postoperatively that led to high hyperopia. regraft was performed considering vitreous leng...

The pharmacokinetics (PK) of ordinary tablets and sustained release capsules of diltiazem hydrochloride in human clinical trials had been studied. The PK of diltiazem hydrochloride delay-onset sustained-release pellet capsules, a new dosage form, has not been reported, although it is very important to clinical use. In this paper, we investigated the PK of diltiazem hydrochloride delay-onset sus...

Malignant pleural effusion (MPE) usually presents in the disseminated and advanced stage of malignancy. Dyspnea is the debilitating symptom which needs palliation in these patients. Various modalities are available in the management of MPE. Careful consideration of the patient's expected survival and quality of life is needed when deciding the optimum treatment modality in such patients. In thi...

BACKGROUND Though the possibility of using malignant pleural effusions (MPEs) as alternatives for metastatic pleural tumor tissues (MPTTs) in epidermal growth factor receptor (EGFR) mutation test has been examined, due to the lack of studies comparing the results in matching MPEs and MPTTs, the clinical value of MPEs for advanced adenocarcinoma patients with pleural effusions is not confirmed. ...