no abstract

leigh syndrome is a severe progressive neurodegenerative disorder with different clinical presentationsthat usually becomes apparent in the first year of life and rarely in late childhood and elderly years. it is causedby failure of mitochondrial respiratory chain and often results in regression of both mental and motor skills and might even lead to death. in some of the inherited neurodegenera...

PURPOSE In an investigation of the functional impact of amblyopia in children, the fine motor skills of amblyopes and age-matched control subjects were compared. The influence of visual factors that might predict any decrement in fine motor skills was also explored. METHODS Vision and fine motor skills were tested in a group of children (n = 82; mean age, 8.2 +/- 1.7 [SD] years) with amblyopi...

To investigate the prognostic values of clinical factors 72 h within traumatic cervical spinal cord injury (TCSCI). Data were extracted from the medical materials of 57 TCSCI cases. AIS was used as the outcome measure and divided into dichotomous variables by two methods, i.e. "complete(AIS = A)/incomplete(AIS ≠ A) SCI" and "motor complete(AIS = A or B)/incomplete(AIS ≠ A and B) SCI". Relations...

The main purpose of this paper is to apply the Fuzzy based General Regression Neural Network (FGRNN) to the speed control of induction motor. A General Regression Neural Network (GRNN) is adopted to estimate the motor speed and thus provide a sensorless speed estimator system. The performance of the proposed FGRNN speed controller is evaluated for a wide range of operating conditions for induct...

OBJECTIVE This study investigated the contribution of perceptual-motor dysfunction and cognitive planning problems to the quality or speed of handwriting in children with handwriting problems (HWP). METHOD Twenty-nine children with HWP and 20 classroom peers attending regular schools (grade 2 and grade 3) were tested with regard to visual perception, visual-motor integration, fine motor coord...

In humans, it is generally not possible to use invasive techniques in order to identify brain activity corresponding to activity of individual muscles. Further, it is believed that the spatial resolution of non-invasive brain imaging modalities is not sufficient to isolate neural activity related to individual muscles. However, this study shows that it is possible to reconstruct muscle activity...

OBJECTIVE To assess the relationship between clinically assessed Upper Motor Neuron (UMN) disease in Amyotrophic Lateral Sclerosis (ALS) and local diffusion alterations measured in the brain corticospinal tract (CST) by a tractography-driven template-space region-of-interest (ROI) analysis of Diffusion Tensor Imaging (DTI). METHODS This cross-sectional study included 34 patients with ALS, on ...

BACKGROUND The age standardised death rate from motor neuron disease (MND) has increased from 1.29 to 2.74 per 100,000, an increase of 112.4% between 1959 and 2013. It is clear that genetics could not have played a causal role in the increased rate of MND deaths over such a short time span. We postulate that environmental factors are responsible for this rate increase. We focus on lead additive...