23 24 It is well recognized that the brain uses sensory information to accurately 25 produce motor commands. Indeed, most research into the relationship between 26 sensory and motor systems has focused on how sensory information modulates 27 motor function. In contrast, recent studies have begun to investigate the reverse: 28 how sensory and perceptual systems are tuned based on motor function,...

A fundamental problem faced by humans is learning to select motor actions based on noisy sensory information and incomplete knowledge of the world. Recently, a number of authors have asked whether this type of motor learning problem might be very similar to a range of higher-level decision-making problems. If so, participant behaviour on a high-level decision-making task could be predictive of ...

It is well recognized that the brain uses sensory information to accurately produce motor commands. Indeed, most research into the relationship between sensory and motor systems has focused on how sensory information modulates motor function. In contrast, recent studies have begun to investigate the reverse: how sensory and perceptual systems are tuned based on motor function, and specifically ...

There are several conflicting evidences showing the effect of morphine on learning and memory processes. In the present study the effect of chronic morphine administration on passive avoidance, active avoidance and spatial learning and memory of morphine dependent male rats using Passive Avoidance shuttle box and Morris Water Maze tasks were investigated, respectively. Male rats received morphi...

Previous work has demonstrated differential changes in early somatosensory evoked potentials (SEPs) when motor learning acquisition occurred in the presence of acute pain; however, the learning task was insufficiently complex to determine how these underlying neurophysiological differences impacted learning acquisition and retention. To address this limitation, we have utilized a complex motor ...

Motor learning is important throughout life for acquisition and adjustment of motor skill. The extent of motor learning may be modulated by the history of motor cortex activity, but little is known which metaplasticity rule (homeostatic vs nonhomeostatic) governs this interaction. Here, we explored in nine healthy adults the effects of three different paired associative stimulation (PAS) protoc...