Among 17786 karyotyres performed in our center,during 18 years (1357-1375),1300(7.3%) cases of chromosome 21 aberration,including 1284(98.77%) of Down syndrome have been detected.1191 of cases (92.76%) born free trisomy 21:61 cases (4.75%) revealed translocation and 32 cases (2.4%) showed mosaic pattern.among the pateints,59 had robertsonian translocation,2 had translocation between chromosome ...

objective: the purpose of this study was to examine the impact of early family-centered psychological and educational interventions on adaptive behaviors in children with down syndrome (ds). method: utilizing an experimental pretest-posttest control group design, parents of 36 children with ds were selected in isfahan. vineland adaptive behavior scale was used to assess adaptive behavior. resul...

purpose: this research aimed to study the effect of 8 weeks core stability training on static balance of the children with down syndrome. methods: a total of 16 children with down syndrome from rehabilitation center of noor abad city were selected and randomly divided into 2 groups of control (n=8) and experimental (n=8). at the pretest and posttest, subjects’ static balances were evaluated by ...

We recently observed an increased frequency of binucleated micronucleated lymphocytes in women who had a Down syndrome (DS) child before 35 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from chromosomal malsegregation events, including chromosome 21 malsegregation. That study indicated that women who have a DS child at a young...

the photoanthropometric method was used to study the facial features in 136 iranian children with down syndrome, aged 4 to 14 years. nineteen parameters were investigated and compared to an age related control group of 100 normal iranian children. the obtained measurements were related to reference values in the same faces. the normal range was defined by age related index values between the 20...

This study presents a preliminary exploration of emotion regulation in a sample of 20 children (ages 3-18 years) with Down Syndrome. Three aspects of emotion regulation (modulation, organization, flexibility) were predicted from emotion variables (affect intensity, affective expression, and autonomy-curiosity and motivation) in backward regression models. Emotion regulation was rated by mothers...