This review is written to fulfill the need of a comprehensive guide for the manufacture of porous polymer particles. The synthesis section discusses and for the first time compares microfluidics, membrane/microchannel, suspension, dispersion, precipitation, multistage polymerizations and a few other less known methods, microfluidics being in greater detail. The comparison includes on one hand s...

Synthesis of monodisperse small Au nanoparticles in a controllable manner is of great importance for fundamental science and technical applications. Here, we report a "precursor continuous-supply" strategy for controllable synthesis of 0.9-3.3 nm Au nanoparticles with a narrow size distribution of 0.1-0.2 nm, using a weak reductant to slow-down the reducing rate of AuClPPh(3) precursor in ethan...

Abstract GFP fusion-based fluorescence-detection size-exclusion chromatography (FSEC) has been widely employed for membrane protein expression screening. However, fused itself may occasionally affect the and/or stability of targeted protein, leading to both false-positive and false-negative results in Furthermore, fusion technology is not well suited some proteins, depending on their topology. ...

When used for emulsion production, microfluidics are known their low energy usage and droplet monodispersity. However, current throughputs need to be improved realize larger scale microfluidic production. Here, we present the upscaled device called Multi EDGE, which use produce 10-µm hexadecane droplets in 0.5 wt% SDS solution at 0.3 m3/m2h a proof of concept study. The design dispersed phase s...

A series of low mass organic gelators (LMOGS) 1 to 6 whose chemical structures have in common an orthodialkoxyarene feature was prepared in order to compare the shape of their fibrillar network as investigated by small-angle neutron scattering (SANS) experiments. All members of the family exhibit a pronounced tendency to bundle formation by merging isolated fibers in extended packets of average...

Three-dimensional crystals were obtained for the membrane domain of the human erythrocyte anion exchanger (AE1, Band 3). Protein homogeneity and stability and the delicate balance between the detergent used and the amount of phospholipids copurifying are critical to the formation of three-dimensional crystals of the AE1 membrane domain. While deglycosylation improved the protein homogeneity, it...

Anisotropic nanoparticles can provide considerable opportunities for assembly of nanomaterials with unique structures and properties. However, most reported anisotropic nanoparticles are either difficult to prepare or to functionalize. Here we report a facile one-step solution-based method to prepare anisotropic DNA-functionalized gold nanoparticles (a-DNA-AuNP) with 96% yield and with high DNA...

Host-guest assembly in droplet-based microfluidics opens a new avenue for fabricating supramolecular hydrogel microcapsules with high monodispersity and controlled functionality. In this paper, we demonstrate a single emulsion microdroplet platform to prepare microcapsules with supramolecular hydrogel skins from host molecule cucurbit[8]uril and guest polymer anthracene-functionalized hydroxyet...

The efficiency of multidentate ligands as digestive ripening (DR) agents for the preparation of monodisperse Au nanoparticles (NPs) was investigated. This systematic investigation was performed using ligands possessing one, two, or three thiol moieties as ligands/DR agents. Our results clearly establish that among the different ligands, monodentate ligands and the use of temperature in the rang...

Well dispersed silver nanoparticles (AgNPs) with narrow size distribution have been grown in organic solvent propylene glycol monomethyl ether acetate (PGMEA) by pulsed laser ablation techniques. The presence of AgNPs in PGMEA solvent gives rise to an enhancement of the absorption and nonlinear optical properties due to the surface plasmon resonance induced by AgNPs. The shape and density of th...