Momordica charantia is a well known plant in Asia including India which posses wide range of pharmacological activities. These drugs have been used in India as folk remedy in the form of decoctions and infusions to treat bacterial infections and also claimed to be an effective against variety of skin conditions like psoriasis, acne, wounds etc. The present investigation is carried out to study ...

Hyperglycemia is a pathological condition associated with prediabetes and diabetes. The incidence of prediabetes and diabetes is increasing and imposes great burden on healthcare worldwide. Patients with prediabetes and diabetes have significantly increased risk for cardiovascular diseases and other complications. Currently, management of hyperglycemia includes pharmacological interventions, ph...

Momordica charantia is a monoecious plant of the Cucurbitaceae family that has both male and female unisexual flowers. Its unique gynoecious line, OHB61-5, is essential as a maternal parent in the production of F1 cultivars. To identify the DNA markers for this gynoecy, a RAD-seq (restriction-associated DNA tag sequencing) analysis was employed to reveal genome-wide DNA polymorphisms and to gen...

The juices of leaves and stem of Mentha piperita (peppermint), skin and seeds of Pisum sativum (garden pea), skin and pulp of Momordica charantia (bitter melon) were screened for antibacterial activities against 56 isolates belonging to 11 different species of Gram-negative bacilli: Escherichia coli (19), Klebsiella pneumoniae (11), Pseudomonas aeruginosa (9), Salmonella typhi (3), Salmonella p...

In present study, the effect of alcoholic extract of Momordica charantia, Aegle marmelos and Eugenia jambolana was studied on serum glutamic oxaloacetate transminase and serum glutamic pyruvate transminase activities and on serum urea, total protein and albumin concentrations of streptozotocin diabetic rats. Diabetes in rats was induced by single dose of streptozotocin (30 mg/kg i. p.). On conf...

Powdered whole Aloviordica charantia fruit (bitter gourd) was tried on eight patients suffering from uncomplicated maturity-onset diabetes. The patients were told to take the, powdered drug in milk twice daily at the rate of 50 mg/kg body weight, to continue on the carbohydrate deficient diet as before, and not to take any other medication. The results obtained show that the drug produced a con...

The effects of blanching, freezing, and frozen storage on the retention of radical-scavenging activity (RSA), total phenolics, and ascorbic acid in bitter gourd were investigated. Blanching of sliced bitter gourd resulted in considerable losses of RSA and total phenolics, and most extensively, of ascorbic acid. In the subsequent frozen storage at -18 degrees C, RSA and total phenolic content of...

Antifeedant and toxic effects of leaf extracts of Syzygium cumini L., Ocimum basilicum L., Luffa aegyptica Mill., Eichhornia crassipes Mart., Tamarindus indica L., Terminalia catappa L., Limonia acidissima L., Murraya koenigii L., Breynia retusa (Dennst.)., Jatropha curcas L., Tectona grandis L., Momordica charantia L., Mangifera indica L., Ricinus communis L., and the seed extract of Madhuca i...

Prior to the availability of chemotherapeutic agents, dietary measures, including traditional medicines derived from plants, were the major forms of cancer treatment. One such plant is Momordica charantia (Family: Cucurbitaceae), whose fruit is known as corilla or bitter gourd/melon. M. charantia possesses anti-carcinogenic properties and it can modulate its effect via xenobiotic metabolism and...

Ulam refers to a group of traditional Malaysian plants commonly consumed as a part of a meal, either in the raw form or after a short blanching process. Many types of ulam are thought to possess blood glucose-lowering properties, but relatively little is known on the effectiveness of ulam in modulating blood glucose levels in humans. This review aims to systematically evaluate the effectiveness...