An electrochemical sensor based on a molecularly imprinted polymer membrane (MIP) was developed. The prepared by electropolymerization of o-phenylenediamine (O-PD) the surface glassy carbon electrode (GCE), modified AuNPs@covalent organic framework (COF) microspheres with ascorbic acid (AA) as template molecule. First, ultrasmall polyvinylpyrrolidone (PVP)-coated AuNPs were chemical reduction m...

Here we introduce microelectrospotting as a new approach for preparation of protein-selective molecularly imprinted polymer microarrays on bare gold SPR imaging chips. During electrospotting both the gold chip and the spotting tip are electrically connected to a potentiostat as working and counter electrodes, respectively. The spotting pin encloses the monomer-template protein cocktail that upo...

In the current study, piezosensors based on molecularly imprinted polyimides with imprints of potassium sorbate and sodium benzoate were obtained. Molecularly Imprinted Polymers (MIPs) synthesized using a polyimide non-covalent imprinting technique. It was established that use 0.1 g/mL template concentration at thermochemical stage led to formation maximum number molecular film surface. Using s...

In this study, we synthesized Fe(3)O(4) magnetic nanoparticles coated estrone-imprinted polymer with controlled size using a semi-covalent imprinting strategy. In this protocol, the estrone-silica monomer complex (EstSi) was synthesized by the reaction 3-(triethoxysilyl)propyl isocyanate with estrone, where the template was linked to the silica coating on the iron oxide core via a thermally rev...

Biodegradable polymer nanoparticles are promising carriers for targeted drug delivery in nanomedicine applications. Molecu- lar imprinting is a potential strategy to target polymer nanoparticles through binding of endogenous ligands that may promote recognition and active transport into specific cells and tissues. However, the lock-and-key mechanism of molecular imprinting requires relatively r...

The aim of this work was to investigate the possibility of employing semi-covalent molecularly imprinted polymers (MIPs) as a controlled release device for ibuprofen and naproxen in biological fluids, especially gastrointestinal ones, compared to non imprinted polymers (NIPs). The carboxyl groups of ibuprofen and naproxen were converted to vinyl ester group by reacting ibuprofen and vinyl aceta...

Mycotoxins are a very diverse group of natural products produced as secondary metabolites by fungi. Patulin is produced by mold species normally related to vegetable-based products and fruit, mainly apple. Its ingestion may result in agitation, convulsions, edema, intestinal ulceration, inflammation, vomiting, and even immune, neurological or gastrointestinal disorders. For this reason, the Eur...

Molecular imprinting technique is used for preparing molecularly imprinted polymer (MIP) membranes of desired recognition site, selectivity and porosity. The novelty of present work is to use a new approach for preparing imprinted monolith membrane, to study the effect of membrane porosity generated due to molecular imprinting on irreversible thermodynamical characteristics like membrane potent...

This article presents a work aiming at thermodynamically and kinetically interpreting the specific sorption and recognition by a molecularly imprinted polymer. Using Boc-L-Phe-OH as a template, the imprinted material was prepared. The result indicates that the prepared polymer can well discriminate the imprint species from its analogue (Boc-D-Phe-OH), so as to adsorb more for the former but les...