In this paper we formally describe the hybrid integrator-gain system (HIGS), which is a nonlinear integrator designed to avoid limitations typically associated with linear integrators. The HIGS keeps sign of its input and output equal, thereby inducing less phase lag than integrator, much like famous Clegg integrator. achieves reduced by projection controller dynamics instead using resets state...

The nucleus in eukaryotic cells is a highly organized and dynamic structure containing numerous subnuclear bodies. The morphological appearance of nuclear bodies seems to be a reflection of ongoing functions, such as DNA replication, transcription, repair, RNA processing and RNA transport. The integrator complex mediates processing of small nuclear RNA (snRNA), so it might play a role in nuclea...

The appropriate timing of flowering is crucial for the reproductive success of plants. Hence, intricate genetic networks integrate various environmental and endogenous cues such as temperature or hormonal statues. These signals integrate into a network of floral pathway integrator genes. At a quantitative level, it is currently unclear how the impact of genetic variation in signaling pathways o...

In this paper a very low-noise low-power correlated double sampled integrator has been presented. For attenuating the sampling thermal noise, two large capacitors are well incorporated in the integrator with no using large sampling and integrating capacitors that are necessary in ordinary integrators. The integrator is used in the front-end of a 24 bit, forth-order single-loop single-bit Delta-...

At the Institution of Physics in Lund quantification of rare isotopes is being conducted with the method of Accelerator Mass Spectrometry (AMS). The procedure involves cycling magnetic fields in two large dipole magnets. The magnets consist of large coils with unlaminated iron cores. These cores give rise to eddy currents which make the magnets difficult to control. To improve the precision of ...

In this paper, we investigate the parameters affecting Total Harmonic Distortion (THD) and Power Supply Rejection Ratio (PSRR) in PWM Class D Amplifiers (CDAs) on the basis of linear models with feedback. From our mathematical analysis, we show that the THD of a PWM Class D amplifier with feedback can be improved by increasing the gain of the integrator through adding another amplifier at the o...

Grid-interactive power converters are normally synchronized to the grid using phase-locked loops (PLLs). The performance of the PLLs is affected by the non-ideal conditions in the sensed grid voltage such as harmonics, frequency deviations and dc offsets in single-phase systems. In this paper, a single-phase PLL is presented to mitigate the effects of these non-idealities. This PLL is based on ...

This paper presents a recent development of PID controllers. The proposed controller design aims to overcome the drawbacks of classical PID controller, such as: integrator windup due to the saturation in the actuator and the slow response to reject disturbances. Classical approaches to treat the windup problem in PID controller design are discussed and analyzed such as conditional integration m...

We present a receding horizon control scheme that utilizes a discrete time version of a nonlinear, iterative, projection-based optimization routine. The routine utilizes a projection operator to ensure feasible system trajectories at each iteration of the optimization resulting in valid control signals even when constraints on computation time prevent full convergence. An additional feature of ...

The C-terminal domain (CTD) of RNA polymerase II (RNAPII) is an essential component of transcriptional regulation and RNA processing of protein-coding genes. A large body of data also implicates the CTD in the transcription and processing of RNAPII-mediated small nuclear RNAs (snRNAs). However, the identity of the complex (or complexes) that associates with the CTD and mediates the processing o...