Spinal neurodegeneration is an important determinant of disability progression in patients with primary progressive multiple sclerosis. Advanced imaging techniques, such as single-voxel (1)H-magnetic resonance spectroscopy and q-space imaging, have increased pathological specificity for neurodegeneration, but are challenging to implement in the spinal cord and have yet to be applied in early pr...

To analyze the effect of botox on upper limb spasm after hemiplegia stroke under background rehabilitation training is main objective study. The data was collected from 100 patients with treated in Rehabilitation Medicine Department Zhejiang Hospital May 2020 to June 2022. These were randomly divided into 50 each and included study group control group. received therapy context training, while o...

BACKGROUND Spasticity affects more than 80% of people with multiple sclerosis (MS), affecting activity, participation, and quality of life. Based on an international guideline, an MS spasticity group education and stretching program, MS Spasticity: Take Control (STC), has been developed. OBJECTIVE The objective of this paper is to determine whether STC with home stretching is associated with ...

OBJECTIVE The aim of this study was to elucidate clinical trial efficacy, safety, and dosing practices of abobotulinumtoxinA (ABO) treatment in adult patients with upper limb spasticity (ULS). METHODS A systematic literature review was performed to identify randomized controlled trials and other comparative clinical studies of ABO in the treatment of adult ULS published in English between Jan...

OBJECTIVE To study the efficacy of intrathecal morphine infusion to treat spasticity. SETTING Functional Neurosurgery Division of University of São Paulo, Brazil. METHOD Twelve patients with clinical refractory spasticity were studied. Two females and 10 males, with median age of 34.4 years (20 to 61 ys.). The initial Ashworth scale was 4.6. They were submitted to pump implantation for intr...

background:   the  role of nutrition  in the  progression  of multiple  sclerosis (ms) and  related  complications  such  as fatigue  has been  reported by several studies.  the  aim of this  study  is the  assessment of nutritional  status  and  its relationship with fatigue in multiple sclerosis patients. methods:  this  is  a  cross-sectional study, in which  101 relapsing-remitting ms patie...