OBJECTIVE A cross-sectional study of haptoglobin (Hp) in myasthenia gravis (MG) was designed, with the objective to identify its values and correlate them with different disease status. METHOD 46 patients were enrolled in the study, all having disease severity established according to the quantitative myasthenia gravis strength scores (QMGSS). Based on the functional scale determined by Myast...

We could detect skeletal muscle injury early after an acute exercise bout by measuring creatine kinase (CK, EC 2.7.3.2) MM isoforms in serum. Eleven men performed 120 alternating-arm, eccentric (muscle lengthening) biceps contractions with the intensity of each contraction being 110% of maximal concentric strength--a form of exercise previously shown to cause significant increases of CK in seru...

Actin cytoskeletal reorganization is essential for tumor cell migration, adhesion, and invasion. Cofilin and actin-depolymerizing factor (ADF) act as key regulators of actin cytoskeletal dynamics by stimulating depolymerization and severing of actin filaments. Cofilin/ADF are inactivated by phosphorylation of Ser-3 by LIM kinase-1 (LIMK1) and reactivated by dephosphorylation by Slingshot-1 (SSH...

This paper represents linkage network of queues consisting of biserial and parallel servers linked to a common server in series with a flowshop scheduling system consisting of two machines. The significant transportation time of the jobs from one machine to another is also considered. Further, the completion time of jobs/customers (waiting time + service time) in the queue network is the set...

This paper deals with the study of multi-server queueing model in a fuzzy environment imposition reneging customers. Entry customers system is assumed to be Poisson process and exponential service time distribution under first-come-first-served basis. Specific this investigation derive various performance measures such as queue length, waiting queue, response optimal number servers explicit for...

Abstract We observed the high-mass star-forming region G335.579–0.292 with Atacama Large Millimeter/submillimeter Array (ALMA) at 226 GHz an angular resolution of 0.?3 (?1000 au source distance). hosts one most massive cores in Galaxy (G335–MM1). The continuum emission shows that G335–MM1 fragments into least five sources, while molecular line is detected two sources (ALMA1 and ALMA3). found ev...

The massive young stellar object (MYSO) G358.93-0.03-MM1 showed an extraordinary near-infrared- to (sub-)millimetre-dark and far-infrared-loud accretion burst, which is closely associated with flares of several class II methanol maser transitions, and, later, a 22 GHz water flare. Water provide invaluable insight into ejection events bursts. Although the short timescale flare made it impossible...

Monoclonal antibody CKM-G01 inhibited greater than 99% of the activity of porcine and human creatine kinase(CK)-MM isoenzyme purified from muscle. However, it inhibited only 54% of CK-MM in human serum. Chromatofocusing of serum CK-MM showed that CKM-G01 inhibited 100% of MM3 but not isoform MM1. CKM-G01 inhibited CK-MM2 by 57%. CKM-G01 specifically inhibited only the original CK-M subunit and ...