Objective (s): This study aimed at investigation of preparation and stability study of Mitomycin and Mitomycin loaded nanoliposems and efficacy of the combination of Mitomycin -loaded nanoliposomes and Curcumin versus Mitomycin in suppressing HTB-9 and L929 cell lines, in vitro.Materials and Methods: An HPLC method was validated based on Q2 (R1) International Conference on Harmonization (ICH) g...

You might know the address of IJPR editorial office; it's in Vali-e-Asr Street just about two kilometers from Vanak square. Vali-e-Asr is one of the longest main streets in Tehran. Tehran is one of the biggest capitals in the world with a population of more than 14 million. The earth is home to more than six billion human beings with huge diverse ethnic backgrounds. Starting from the IJPR offic...

You might know the address of IJPR editorial office; it's in Vali-e-Asr Street just about two kilometers from Vanak square. Vali-e-Asr is one of the longest main streets in Tehran. Tehran is one of the biggest capitals in the world with a population of more than 14 million. The earth is home to more than six billion human beings with huge diverse ethnic backgrounds. Starting from the IJPR offic...

After the boom of pharmacological research during the 1950s, mainly as a result of the screening technique, the identification of active molecules, their reshaping by means of pharmaco-chemical drug design, and the creation of extremely efficacious and successful medicines, the pharmaceutical world sought a new source of inspiration. Such biota as the tropical forest, a quantity of plants credi...

the purpose of this paper is to make explicit how companies in pharmaceutical sector can ensure their position in different markets by relying on a sustainable competitive advantages resulted from using a good defined marketing model. various factors are highlighted including high research and development roles and costs, hard government regulation in frame of gmp standard, market analysis tool...

Biodesulfurization of coal has been carried out in batch culture of single strain and mixed culture of sulfur oxidizing bacteria. The pure cultures of Thiobacillus thiooxidans and Thiobacillus ferrooxidans utilized inorganic sulfur content of Malaysian coal. The chemolithotroph bacteria were able to grow on coal and metabolize the coal's sulfur content. The batch cultures of coal with 3-5 perce...

Abstract: The reactive 1:1 intermediate produced in the reaction between cyclohexyl isocyanide and electron- deficient acetylenic esters or dimethyl acetylene dicarboxylate was trapped by 2-cyano-N-(Aryl) acetamides to provides highly functionalized oxopyridine (potential synthetic and pharmaceutical interest )  in  acetonitrile under mild reaction conditions at ambient temperature after 24 h ...

The effects of magnesium stearate (MgSt) and shear stress on flow properties and hydrophobicity are not well known. Blends with different concentrations of magnesium stearate and varying amounts of shear were tested using three different procedures: the FT4 Rheometer test, a tap density analyzer, and the Washburn method, to better understand the relation of lubricant concentration, amount of sh...