Circulating microRNAs have been recognized as promising biomarkers for the detection of lung cancer. The objective of this study was to evaluate miR-10b, miR-1 and, miR-30a in the plasma samples of lung cancer patients to confirm any possible relevance in the early detection of lung cancer. Plasma samples from 47 non-small-cell lung cancer patients and 41 cancer-free subjects were evaluated for...

The daily environmental exposure of humans to plasticizers may adversely affect human health, representing a global issue. altered expression microRNAs (miRNAs) plays an important pathogenic role in plasticizers. This systematic review summarizes recent findings showing the modified miRNAs cancer due Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodolo...

objective(s):micrornas (mirnas) are a class of short rnas that control the biological processes including cell proliferation, apoptosis and development. aberrant expression of mirnas was determined in the different stages of tumor development and metastasis. to study the effect of silibinin on mirnas expression, we evaluated quantitative expression of mir-21 and mir-155 as two oncomirs and seve...

Sommario Il diabete mellito di tipo 2 (DMT2) è una malattia metabolica cronica eterogenea in costante aumento. In questa rassegna, al fine identificare un gruppo microRNA (miRNA) con potenziale applicazione clinica come biomarcatori per la diagnosi, prognosi e selezione terapie personalizzate i pazienti DMT2, abbiamo effettuato ricerca sistematica letteratura, identificando selezionando 10 miRN...

MicroRNAs (miRNAs) are small non-coding RNAs that function as post-transcriptional gene expression regulators. The expression profiling of miRNAs has already entered into cancer clinics as diagnostic and prognostic biomarkers to assess tumor initiation, progression and response to treatment in cancer patients. Recent Studies opened the way for the use of circulating miRNAs as non-invasive diagn...

iterary studies have long been in the habit of investigating the category of the literary from various critical perspectives. Indeed, we have come to expect that a book on literature will contain a critical reflection on the limits of literature, knowing that a simple celebration of literature will obscure more than it will reveal. Such self-criticism is much harder to find in theater studies, ...

Oral contraceptives (OC) are very a widely prescribed therapy for premenstrual symptoms yet, only a limited number of studies have explored the relationship between OC and numerous premenstrual symptoms. The aim of this study was to investigate the differences in retrospectively reported premenstrual symptoms between users and non-users of oral contraceptives. In total 385 women (186 OC-users a...