INTRODUCTION Clear cell carcinoma is a rare low-grade carcinoma that almost exclusively occurs in the minor salivary glands. This tumour is one of the new additions in the recent World Health Organization (WHO) classification of salivary gland tumours. CLINICAL PICTURE A 50- year-old woman presented with a gradually enlarging painless submucosal mass of 3 months' duration over the left side o...

Lymphoepithelial carcinoma (LEC) of salivary gland origin is a rare malignant tumor with morphological characteristics identical to those of undifferentiated nasopharyngeal carcinoma. It has a marked racial predilection for Inuit and Southeast Asian populations. An association between LEC and Epstein-Barr virus (EBV) infection has previously been reported. LEC most frequently affects the paroti...

Basal cell adenoma (BCA) of the salivary glands is a rare benign tumor resembling pleomorphic adenoma, but with a prominent basaloid cell layer. The majority of these tumors arise in the parotid glands and account for only 1% of all salivary gland epithelial tumors. We report one such case of a swelling in the floor of the mouth in a 55-year-old female where BCA is the most likely diagnosis; ho...

Among the more common types of intraoral minor salivary gland neoplasms are pleomorphic adenoma, basal cell adenoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma. These minor salivary gland neoplasms share similar morphologic features and to a large extent immunohistochemical findings. Differentiation between these benign and malignant neoplasms is often predicated on the...

BACKGROUND Myoepitheliomas are uncommon salivary gland neoplasms consisting entirely or predominantly of cells with myoepithelial phenotype. They commonly involve the parotid gland and the minor salivary glands of the palate. AIM A case of plasmacytoid myoepithelioma of the hard palate is described. CASE DESCRIPTION AND RESULTS A 55-year-old woman presented to her oral surgeon with a tumor ...

BACKGROUND AND AIMS Salivary gland tumors are rare and specific lesions. There are differences in the incidence and frequency of salivary tumors in both minor and major salivary glands in different countries. This study was carried out to determine the prevalence of major and minor salivary gland tumors in Ahvaz in the south of Iran. MATERIALS AND METHODS All the cases, recorded in Imam Khome...

Human kallikrein 6 (hK6), also known as zyme/protease M/neurosin), is expressed in many normal glandular tissues. The aim of this study was to determine whether hK6 is expressed in salivary gland tissues and salivary gland tumors (both benign and malignant), using an immunohistochemical method. Pleomorphic adenomas (PA), adenoid cystic carcinomas, polymorphous low-grade adenocarcinomas, acinic ...

Pleomorphic adenoma also known as “mixed tumor” is the most common neoplasm in major salivary glands. It is a benign tumor arises from the parotid gland in 84% of cases and represents 45% of parotid gland tumors [1]. Only 6.5% are found in the minor salivary glands [2]. Salivary gland tumors occurring in ectopic sites are rare and poorly understood; sometime we can find heterotopic tissue arisi...

BACKGROUND Neonatal hemochromatosis (NH), a rare disorder seen in newborns, is defined as liver failure with extrahepatic iron deposition that spares the reticuloendothelial elements. This disorder is considered the pathologic end point of a variety of diseases that result in prenatal liver failure, and mortality without aggressive treatment is common. However, ready diagnosis remains a problem...