Enclomiphene, an isomeric component of clomiphene citrate, acts antagonistically to the oestradiol receptor at the hypothalamus level, inhibiting both negative and positive feedback, and resulting in the induction of ovarian stimulation and suppression of ovulation. The minimal ovarian stimulation protocol takes full advantage of these characteristics of clomiphene citrate. Administration of 50...

In a large distributed system it is often infeasible or even impossible to maintain a model of the whole system. Instead, several spatially distributed local models of the system have to be used to detect possible faults. Traditional diagnostic tools cannot handle such a set of spatially distributed local models. A Multi-Agent System of diagnostic agents, where each agent has a model of a subsy...

Frozen embryo transfers (FETs) have become increasingly popular in assisted reproductive technologies (ART) due to advancements cryopreservation techniques and the implementation of "freeze-all" strategy. The choice between artificial (AC) or natural (NC) cycles for FET preparation has been a subject debate, considering factors such as endometrial receptivity, flexibility scheduling, pregnancy ...

BACKGROUND Poor ovarian response to controlled ovarian stimulation is one of the most important interest points in assisted reproduction. Mild ovarian stimulation seems to be preferable to high dose of FSH regimens in women with a history of poor ovarian response in previous protocol. Clomiphene citrate and letrozole alone or in combination with FSH have been used in mild ovarian stimulation pr...

Some researchers have long been interested in reconstructing natural insects into steerable robots or vehicles. However, until recently, these so-called cyborg insects, biobots, or living machines existed only in science fiction. Owing to recent advances in nano/micro manufacturing, data processing, and anatomical and physiological biology, we can now stimulate living insects to induce user-des...

Therapeutic effects of functional electrical stimulation (FES) cycling for persons with spinal cord injury (SCI) are limited by high rates of muscular fatigue. FES-cycling performance limits and surface mechanomyography (MMG) of 12 persons with SCI were compared under two different stimulation protocols of the quadriceps muscles. One strategy used the standard "co-activation" protocol from the ...

Abstract Progressive primary aphasia (PPA) designates a group of neurodegenerative diseases affecting language processing for which no pharmacologically effective treatment exists. PPA presents in three different variants with distinct and brain damage areas: logopenic PPA, non-fluent/agrammatic semantic (PPA-sv). We here present an interim analysis sham-controlled randomized double-blind proto...