The stomach of newborn pig contains a proteinase that is immunologically closely related to calf chymosin (rennin) (EC 3.4.23.4.). None of the pepsins from the stomach of adult pig is present in the newborn pig. Pig chymosin has optimal general proteolytic activity around pH 3.5. The ratio of milk-clotting activity to general proteolytic activity is about 30--70 times higher than that of pylori...

Abstract Genetically engineered chymosin from the tree shrew ( Tupaia belangeri chinensis ) has been obtained and partially characterized for first time. The target enzyme was produced in Escherichia coli , strain BL21(DE3). It shown that recombinant coagulates cow milk Bos taurus ). total specific milk-clotting activity of 0.7–5.3 IMCU/mL 8.8–16.6 IMCU/mg. nonspecific proteolytic relation to b...