Folliculotropic mycosis fungoides is a variant of cutaneous T-cell lymphoma with distinct clinicopathological features. We describe here the clinical presentation, pathology findings and treatment outcome in 15 Norwegian patients. All patients were diagnosed between 1997 and 2010 at Oslo University Hospital. A spectrum of skin lesions, both typical and atypical, such as leonine facies, acneifor...

Fig. 1. Erosions on the forehead. Fig. 2. Erosions, milia and scarring on the dorsum of the hand. Sir, Porphyria cutanea tarda (PCT) is a vesiculobullous skin disorder of heme biosynthesis in which there is an enzyme defect of uroporphyrinogen decarboxylase (Uro-D), leading to accumulation of porphyrins mainly in urine but also in stool and plasma. Pseudoporphyria is clinically similar to PCT, ...

Inherited skin fragility disorders comprise a group of disorders, mainly designated as epidermolysis bullosa (EB), that are characterised by mechanical induced blistering and erosions of the skin and mucous membranes caused by mutations of gene coding for protein components of the dermal–epidermal junction zone. Patients with EB experience various degrees of recurrent skin blistering, widesprea...

A number of innocent rashes occurs in neonates. They are usually transient and self limited and thus require no therapy but early recognition is important to distinguish these lesions from more serious disorders. In this study, our purpose was to determine the frequency of birthmarks in Iranian neonates. The presence of various types of birthmarks was determined in 503 Iranian neonates under 72...

The aim of this study is to assess the frequency of both physiological and pathological cutaneous lesions in first seven days of life in a tertiary care hospital of western Uttar Pradesh. Overall 500 neonates either inborn or attending paediatric OPD/ clinic and delivered in the hospital were included in the study. The study took 6 months, consent from parents of those neonates were taken. Clin...

Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3). Coexistence of autoantibodies of bullous pemphigoid and pemphigus in a patient is rare. A 25-year-old male patient was admitted to our hospital, reporting a 3-month history of multiple p...

Dystrophic epidermolysis bullosa simplex (DEB) is a phenotypically diverse inherited skin fragility disorder. It is majorly manifested by appearance of epidermal bullae upon friction caused either by physical or environmental trauma. The phenotypic manifestations also include appearance of milia, scarring all over the body and nail dystrophy. DEB can be inherited in a recessive or dominant form...

efficacy. These lesions are rarely selflimiting, and recurrences are common. We describe a 25-year-old woman with no relevant history who consulted for asymptomatic, flesh-colored papules of 1-2 mm, distributed on the anterior area of the neck and neckline (Figure 1). The symptoms started 10 years earlier on the lower eyelids, gradually spreading to the abdomen, neck, and neckline, with outbrea...

INTRODUCTION Approved in 2011, vemurafenib is a selective serine/threonine kinase inhibitor directed against the V600E mutation in the BRAF gene. This drug is often used in dermatology as a targeted therapy for metastatic or unresectable melanomas, for which about 50% have this mutation. Other tumors possessing the V600E mutation are targets for this therapy. The commonly reported adverse effec...

Case report A 30 year old man of Indian extraction presented at a dermatology clinic with a six month history of photosensitivity. After being exposed to summer sunshine in London in the middle of the day he would develop erythema and itching of the hands and ears the same evening and blistering the following day. He had had extensive vitiligo for 20 years, but the photosensitivity also affecte...