IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes were determined in sera from patients with mild, moderate or severe acne and from a control group. Titres specific to S. epidermidis were all within the same range and did not differ between groups. The titres of IgG subclasses to specific to P. acnes did vary between groups. IgG1 and IgG3 were significantly highe...

A number of topical agents are effective for the treatment of mild to moderate acne, but patients often do not use their medications as prescribed. Medication use increases around the time of office visits, but frequent office visits may not be a practical way to increase compliance. Because adolescents use the Internet regularly, we tested whether a weekly Internet-based communication could im...

BACKGROUND Subcision is a procedure that has been reported to be beneficial in treatment of acne scars. OBJECTIVE This stady aims to assess the efficacy of subcision in the treatment of rolling acne scars and evaluate a novel subdermal filler 'absorbable plain catgut suture' with subcision. METHODS Twenty-two patients with rolling acne scars underwent subcision, 20 of whom completed treatme...

Acne vulgaris is one of the most common dermatologic diseases, affecting teenagers as well as adults, with a possibility to cause long-lasting psychosocial and physical effects. Since acne is a chronic inflammatory skin disorder, a long-lasting combined treatment as well as maintenance therapy are advised. Conventional treatments such as topical and oral medications are often associated with po...

Background: Topical retinoids are considered the first-line approach in the treatment of comedonal or mild inflammatory acne. However local tolerability of topical retinoids could be a limiting factor regarding their widespread clinical use in this setting. A new topical formulation containing two vitamin A derivatives (retinol and hydroxypinacolone retinoate, carried in a patented glycospheres...

Objective: To evaluate the characteristics of post-adolescent male patients with acne in terms onset condition, its clinical course and severity, behaviors associated severity.
 Materials Methods: A prospective, cross-sectional study was conducted on adult males who visited Siriraj Hospital, Thailand. All aged 21 years older were enrolled. Diagnoses physical examinations performed by derma...

BACKGROUND Topical retinoids are considered first-line therapy in the treatment of acne vulgaris, yet can be associated with cutaneous irritations. Combination therapy with natural preparations could be effective in treatment and decreasing adverse events. OBJECTIVE The aim of this study was to compare the efficacy and safety of the combination of tretinoin (TR) cream (0.05%) and Aloe vera to...

Objective: Acne rosacea is a difficult to treat disease and current treatments remain unsatisfactory. Our aim was to assess and present the photographic evaluation of the effectiveness and tolerability of azelaic acid 15 % gel for the treatment of acne rosacea. Methods: Healthy male and female adult outpatients (>18 years of age) with mild to moderate acne rosacea. All patients were instructed ...