Migraine is a common neurological disorder characterized by painful episodes sometimes preceded by transient neurological symptoms and reversible defined migraine aura. Rarer forms of migraine are hemiplegic migraine, familial and sporadic, the retinal migraine and migraine equivalents. For the two most common forms of migraine with and without aura, the prevalence appears to be higher in femal...

BACKGROUND Migraine is one of the most common and debilitating neurological problems. Although numerous preventive drugs are used to treat migraine, their complications are unavoidable. Application of herbal medicine, especially well-known medicinal plants, to treatment of chronic diseases, like migraine, could be effective. Coriandrum sativum L. (C. sativum) fruit is one of the most commonly p...

Background Although the development of effective and safe treatments for prophylaxis of migraine headaches represents an important public health concern, only a few medications have been approved by the specific treatment of patients with migraine. We aimed to compare the efficacy of cinnarizine with propranolol in the prophylaxis of pediatric migraine headache. Materials and Methods  In a Ran...

OBJECTIVE Recurrent headaches and ADHD are prevalent in the pediatric population. Herein, we assess if ADHD is comorbid to headaches overall, to headache subtypes (e.g., migraine), and to headache frequency. METHOD Informed consent and analyzable data were obtained for 5,671 children aged 5 to 12 years (65.9% of the target sample). Parents and teachers were interviewed using validated questio...

BACKGROUND Although mental stress is commonly considered to be an important trigger factor for migraine, experimental evidence for this belief is yet lacking. OBJECTIVE To study the temporal relationship between changes in stress-related parameters (both subjective and objective) and the onset of a migraine attack. METHODS This was a prospective, ambulatory study in 17 migraine patients. We...

Studies suggest that more than one-third of persons with migraine need preventive therapy; however, only 3 to 13 percent use it. The American Academy of Neurology (AAN) and American Headache Society (AHS) recently reviewed studies published since 2000 to determine which therapies reduce migraine frequency or severity, or reduce the number of days with migraine. These guidelines do not address o...

Migraine is a common clinical disorder, quite disabling and affecting the quality of life in majority of patients. The visual aura is the commonest among all types of aura. Various types of migraine aura described in the literature are photopsia, fortification spectra, scotoma, visual distortion, haemianopia and metamorphsia. The epileptic visual aura differs from aura associated with migraine ...

BACKGROUND Migraine is recognised increasingly as a risk factor for ischaemic stroke in women of childbearing age. Migraine with aura poses a higher risk than migraine without aura. OBJECTIVE To investigate further the effect of duration, frequency, recency, and type of migraine on the risk of ischaemic stroke. METHODS Additional analyses of a previously reported multicentre case-control st...