BACKGROUND The purpose of this study was to evaluate the efficacy of prenatal ultrasonography and Doppler sonography in detecting isolated ventricular septal defects (VSDs) in a late-second-trimester population. METHODS Fetal echocardiography, Doppler ultrasound, and biometry were used to evaluate 2,661 singleton fetuses (1,381 male fetuses and 1,280 female fetuses) between 1 August 2006 and ...

Objective: To assess the impacts of dexamethasone given to the mother on fetal Doppler flow velocity waveforms of both umbilical and fetal middle cerebral arteries in pregnancies with normal fetoplacental vascular resistance. Study Design: Prospective Study. Patients and Methods: Pregnant women between 28 weeks and 34 weeks gestation at risk of preterm labour, Preterm birth was anticipated on t...

Introduction: Based on our previous findings, the treatment of stem cells alone or in combination with thyroid hormone (T3) and mild exercise could effectively reduce the risk of stroke damage in young mice. However, it is unclear whether this treatment is effective in aged or middle-aged mice. Therefore, this study designed to assess whether combination of Bone Marrow Stromal Cells (BMSCs) wit...

Neurologic deficits that occur simultaneously with or subsequent to internal carotid artery occlusion may be influenced by the adequacy of the intracerebral collateral circulation. Transcranial Doppler ultrasonography was used to evaluate mean middle cerebral artery blood velocity and blood flow in major collateral arteries in 78 patients, including 39 patients with 40 internal carotid artery o...

Background: β-thalassemia, a severe form of anemia, is an inherited blood disorder characterized by growth retardation, splenomegaly, and bone abnormalities. Complications related to treatment-induced iron overload also affect the quality of life of patients with major β-thalassemia. Some recent studies indicated cerebral hemodynamic disorders and increased risk of stroke in these patients. The...

Objective: To evaluate the value of Doppler velocimetry of umbilical and middle cerebral arteries and amniotic fluid volume in the surveillance of post term pregnancies. Design: Cross sectional study. Setting: Kasr El-Aini Hospital. Materials and Methods: Forty pregnant ladies with a gestational age of more than 41 weeks were compared to 40 pregnant ladies with gestational age ranging from 37 t...

BACKGROUND AND PURPOSE Treatment of ischemic stroke by activation of endogenous plasminogen using tissue plasminogen activator is limited by bleeding side effects. In mice, treatment of experimental ischemic stroke with activated protein C improves outcomes; however, activated protein C also has bleeding side effects. In contrast, activation of endogenous protein C using thrombin mutant W215A/E...