The full-length cDNA sequence for metalloprotease (MEP) of Arthroderma gypseum (one of the teleomorphs of the Microsporum gypseum complex) was determined by the 5'-rapid amplification of cDNA ends (RACE) and 3'-RACE methods using cDNA as a template. The full-length cDNA sequence of the MEP (2,670 bp) gene was proved to encode 677 amino acids. The amino acid sequence of the A. gypseum MEP gene s...

Antifungal activity of naftifinc (SN 105-843 gel) a napthyle alkyleamine derivative, was measured in vitro against freshly isolated cultures of dermatophytie fungi. Using appropriate concentrations of naftifine, its antifungal activity was compared with the same concentrations of griseofulvin against Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton violaceum, Trichophyton tonsuran...

BACKGROUND AND PURPOSE Superficial mycotic infections have been only poorly described in koalas and there are no reliable mycologically confirmed data regarding clinical isolation of dermatophytes in this animal. We report an 11-year-old female koala, kept in a zoo in Tokyo, Japan, and presenting with hyperkeratotic lesions and scaly plaques on forepaw claws and pads reminiscent of fungal infec...