was attributed to the broncho-pneumonia, but against this explanation was the fact that the administration of oxygen failed to abolish or decrease the cyanosis, whereas the cyanosis usually accompanying bronchopneumonia can be relieved or abolished easily by adding some oxygen to the inspired air." He suggested, on the evidence that he gave, that the haemoglobin was in the form of methaemoglobi...

It has recently been established that nitrosoglutathione is the preferred substrate of the glutathione-dependent formaldehyde dehydrogenase from divergent organisms. Trypanosomatids produce not only glutathione, but also glutathionylspermidine, trypanothione and ovothiol A. The formaldehyde dehydrogenase activity of Crithidia fasciculata was independent of these thiols and extracts possessed ve...

background: although lipid lowering agents as statins are used frequently in hyperlipidemic patients as well as patients with cardiac disease, they could have major hepatic side effects, the aim of this study is to evaluate the safety of statins mainly atorvastatin on liver as estimated by liver aminotransferase assay. m aterials and methods: patients with indication of atorvastatin were includ...

Nitrate is one of the major sources of nitrogen for the growth of plants. It is taken up by plant roots and transported to the leaves where it is reduced to nitrite in the. The main objective of this research was to investigate stimulatory effects of sodium nitrate, potassium nitrate, ammonia and urea on the production/generation of the nitrate reductase mRNA in Triticum aestivum plants. The pl...

PURPOSE To determine the effect of an anaesthetic with antioxidant potential, propofol, on red blood cell (RBC) antioxidant enzyme activities and RBC susceptibility to peroxidative challenge. METHODS Propofol was administered by intravenous bolus (2.5 mg.kg-1) and continuous infusion (36 and 72 ml.hr-1 in nine swine; 216 ml.hr-1 in two swine), to achieve serum concentrations between 5 and 30 ...

BACKGROUND The present study sought to investigate erythrocyte glutathione S-transferases (GST), NADH-Methaemoglobin reductase (NADH-MR) and Na(+)/K(+)-ATPase activities of hypoglycemic rats treated with ethanol/water (1:2 v/v) extract of A. sativa as agent of glycemic control. METHODS Hyperglycemia was induced by a single intra-peritoneal injection of 0.1 mol/L alloxan monohydrate in phospha...

The thioredoxin system is vital in maintaining the cellular redox state and implicated various cancers other diseases. It comprises of reductase, NADPH. Various methods have been developed for detection quantification reductase enzyme. Most these suffer shortfall poor specificity, hence there need to develop more robust specific techniques. Recently, has an increased interest fluorescent probes...

Original Article AIMS AND OBJECTIVES:1. To screen blood donors [n=100] for G6PD deficiency, particularly in males. 2. To determine the frequency of G6PD deficiency in the population tested. MATERIALS AND METHODS: 50 samples of donors' blood from at KIMS Blood Bank. Method of collection of data: The Methaemoglobin reduction test: Principle: Sodium Nitrate oxidises MethHb to Hb and the subsequent...