Metabolomics is a new ‘omics’ discipline, based on the detailed analysis of the host’s metabolic phenotype and the complex metabolic pathways with multiple network interactions. This metabolic fingerprint is considered as the gold standard for the profound understanding of the normal metabolic processes and of the alterations of the normal pathways. This ‘snapshot’ of the metabolic status may b...

BACKGROUND Women who experience menopause are at higher cardiometabolic risk and often display adverse changes in metabolic biomarkers compared with pre-menopausal women. It remains elusive whether the changes in cardiometabolic biomarkers during the menopausal transition are due to ovarian aging or chronological aging. Well-conducted longitudinal studies are required to determine this. The aim...

BACKGROUND Growth failure and delayed puberty are well known features of children and adolescents with inflammatory bowel disease (IBD), in addition to the chronic course of the disease. Urinary metabonomics was applied in order to better understand metabolic changes between healthy and IBD children. METHODS 21 Pediatric patients with IBD (mean age 14.8 years, 8 males) were enrolled from the ...

ISSN 1745-5057 10.2217/WHE.12.31 © 2012 Future Medicine Ltd Women's Health (2012) 8(4), 367–369 were never smokers. Overall, the prevalence of metabolic syndrome increased with age, regardless of smoking or menopausal status. Past smokers had significantly higher odds of metabolic syndrome, regardless of menopausal status. In never smokers, only postmenopausal women demonstrated increased odds ...

Change in metabolic status, defined as a change in the availability of nutrients and energy to the tissues, is a powerful regulator of the reproductive function in small ruminants, especially in genotypes that are not strongly responsive to photoperiod such as the Merino sheep. In this paper, the dynamics of the response of the reproductive axis to changes in metabolic status are reviewed in th...

INTRODUCTION Metabolic acidosis is a common problem in dialysis patients and plays an important role in the pathogenesis of protein-energy malnutrition in these patients. OBJECTIVES To assess the prevalence of metabolic acidosis in hemodialysis and search their association with nutritional status. METHODS A cross-sectional study was performed in hemodialysis patients at a single center. Nut...

Offspring of long-lived families are characterized by beneficial metabolic phenotypes in glucose and lipid metabolism and low 25-hydroxyvitamin D. Although the genetic basis for human longevity remains largely unclear, the contribution of variation at the APOE locus has been repeatedly demonstrated. We aimed to assess whether ApoE isoforms mark the familial longevity status in middle age and su...

INTRODUCTION The nutritional and metabolic status have been related to cancer risk factors as well as to cancer treatment morbimortality. Thus, its assessment is important for developing strategies for the promotion, maintenance and / or recovery of nutritional status and cancer outcome. MATERIAL AND METHODS Several different methods for nutritional assessment in breast cancer patients underg...

Background: The aim of our study was to determine the metabolic profile: glucose, triglycerides (TG), high density lipoprotein (HDL) and cholesterol (CHT) in women undergoing ART (Assisted reproductive technology) cycles and estimate its effect on In Vitro Fertilization (IVF) outcomes Materials and Methods: Forty three women undergoing IVF treatment were included in the study. Patients were all...

BACKGROUND AND AIMS The European 'IMMIDIET' study was designed to evaluate the effect of genetic and dietary habit interactions on cardiovascular disease risk factors in non-diabetic subjects. Copper, zinc and selenium are involved in redox balance and modifications of their homeostasis could be associated with metabolic syndrome. Because few studies have dealt with trace element status in meta...