To cite: Abbas A, Mujeeb AA. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200265 DESCRIPTION A 6-month-old infant presented with a 2-day history of fever, irritability and rashes. On examination, she was febrile, hypotensive and had a purpuric rash covering the face, trunk and extremities along with symmetrical black discolouration of fingers and toes of al...

Meningococcal disease, which is caused by Neisseria meningitidis (N. meningitidis), may present clinically as meningococcemia, meningitis, or with a mixed picture. A 3-year-old girl was admitted to our hospital tender, immobile, hard, hot and erythematous mass measuring 3x4 cm on the left anterior part of neck. The patient diagnosed branchial cleft cyst in side neck regularly followed an otolar...

We present a retrospective analysis of clinical profile of 100 children admitted to a Government hospital at Delhi between April 2005 and December 2006 with group A meningococcal infection. Maximum children presented in late winter and spring. Younger children were less affected (5% children < 1 year). Fever (86%), vomiting (64%) and rash (63%) were the most common presenting symptoms. All chil...

Introduction A 27-year-old woman present with a 3-day history of painful lesions over her fi ngertips associated with a right wrist swelling, yellowish vaginal discharge and fever. Her past medical history was unremarkable. Physical examination revealed haemorrhagic pustules over the left thumb, left middle fi nger (Fig. 1), as well as tender linear erythematous patches overlying the lateral ex...

The benefits of the Integra Dermal Regeneration Template in the management of extensive burn injuries have been well documented. Integra can reduce donor- and graft-site scarring and has been reported to be capable of vascularizing over small areas of exposed bone and tendon. Given these potential advantages, we have used Integra for a variety of other reconstruction applications. We performed ...

Enteric bacilli and meningococci (MGC) both contain potent endotoxins, but purpuric skin lesions indistinguishable from the experimental dermal Shwartzman reaction are much more common during meningococcal bacteremia than during bacteremia with enteric organisms. Highly purified lipopolysaccharides (LPS), virtually free of contamination by protein, RNA, and capsule, were extracted by a modifica...