Dear Editor, Addison's disease (AD) is a potentially life-threatening endocrine disorder caused by adrenocortical insufficiency. A deficiency in Adrenocorticotropic Hormone (ACTH) diminishes the negative feedback to hypothalamic-pituitary axis, leading adenohypophysis secrete elevated levels of plasma ACTH and melanocyte-stimulating hormone. This hormonal alteration results skin mucosal melanin...

Laugier-Hunziker syndrome is a rare idiopathic acquired hyperpigmentation of oral mucosa and lips which is often associated with longitudinal melanonychia. This condition is known to be an entirely benign disease with no systemic manifestations. Herein we report a case of a 54-year-old woman presenting with a 7-year history of asymptomatic oral pigmentation and linear pigmented streaks of sever...