RATIONALE Endometrial cancer patients with lung metastases are rare, and more rarely with long-term management of progesterone after recurrence. PATIENT CONCERNS Informed consent of the patients and their families. DIAGNOSES Endometrial cancer (IVB) (Refer to 2009 FIGO stag of endometrial cancer). INTERVENTIONS the patient was treated with Megestrol Acetate Dispersible Tablets (trade name...

Aromatase Inhibitor(AI) therapy is a crucial treatment for regulating estrogen production that combats breast cancer in postmenopausal patients. Clinical trials have emphasized its importance, as it has surpassed prior efficacy through each succeeding generation of AI and other options like modulators(Tamoxifen) Progestin therapy(Megace/Megestrol Acetate). There big difference between therapies...

Induced molting increases egg quality and egg production and extends the productive life of hens. Molting is accomplished by feed withdrawal, which has received criticism, and alternatives described thus far result in poor postmolt performance. Melengestrol acetate at a dosage of 4 or 8 mg/d, in a balanced diet, leads to reversible regression of the reproductive tract. However, this alternative...

Recent studies (e.g. Blackmore, P. F., Beebe, S. J., Danforth, D. R., and Alexander, N.) (1990) J. Biol. Chem. 265, 1376-1380) have shown that in human sperm, progesterone produces a rapid increase in intracellular free calcium ([Ca2+]i) and an induction of the acrosome reaction (e.g. Osman, R. A., Andria, M. L., Jones, A. D., and Meizel, S. (1989) Biochem, Biophys. Res. Commun. 160, 828-833). ...