Methods We retrospectively reviewed records of our dayhospitalization from 2007 to 2012 for patients with FMF unresponsive to oral treatment who were treated with supplemental 1mg IVC (120 min infusion) once a week. We tabulated records of clinical events: fever, number of attacks per month and CRP levels before and after at least one year of this treatment. Adverse events were also recorded, a...

Mediterranean temporary ponds (MTPs) comprise an endangered habitat with several endemic species that can be found in many countries, mainly in the Mediterranean region but are disappearing at a high rate. For designing optimal conservation and management strategies for the particular ecosystems, appropriate characterization and classification of these ponds is necessary based on the different ...

Familial Mediterranean fever is a recessive autoinflammatory disease that is frequent in Armenians, Jews, Arabs, and Turks. The MEFV gene is responsible for this disease. We looked for MEFV gene variations (polymorphism and mutations) in a population that resides in Central Anatolia, Turkey. DNA was extracted from peripheral blood leukocytes of 802 familial Mediterranean fever patients. Th...

From April 1983 to September 1990, 32 patients with familial mediterranean fever (FMF) were studied. FMF is characterized by short, self-limited, febrile episodes that occur with inflammation of serosal surfaces. Major symptoms include fever and abdominal pain, presenting as acute surgical abdomen. These attacks are associated with considerable morbidity and in some patients lead to unnece...

Familial Mediterranean fever (FMF) is an autosomal recessive disorder that is characterized by sporadic paroxysmal attacks of fever and serosal inflammation. Although it occurs primarily in ethnic groups originating in the Mediterranean region, FMF is not restricted to these groups and is still underdiagnosed in nephrology settings in nonMediterranean countries (1). The disease morbidity is lar...

1. Touitou I. The spectrum of familial Mediterranean fever (FMF) mutations. Eur J Hum Genet 2001;9:473–83. 2. Haskard DO. Accelerated atherosclerosis in inflammatory rheumatic diseases. Scand J Rheumatol 2004;33:281–92. 3. Livneh A, Langevitz P, Zemer D, et al. Criteria for the diagnosis of familial Mediterranean fever. Arthritis Rheum 1997;40:1879–85. 4. Lidar M, Scherrmann JM, Shinar Y, et al...

INTRODUCTION Familial Mediterranean fever (FMF) is the most common auto-inflammatory disease with monogenic (MEditerranean FeVer -MEFV- gene) inherited pattern. It mainly affects ethnic groups living along the eastern Mediterranean Sea: Turks, Sephardic Jews, Armenians, and Arabs [1]. Today FMF is not rare disease in other Mediterranean ethnicities, such as Greeks, Italians, and Iranians. CAS...

Spotted fevers, which are caused by Rickettsia spp. in the spotted fever group (SFG), have been recognized in people for more than a hundred years. The clinical signs are broadly similar in all of these diseases, but the course ranges from mild and self-limited to severe and life-threatening. For a long time, spotted fevers were thought to be caused by only a few organisms, including Rickettsia...

Background: Familial Mediterranean fever (FMF) has episodic or subclinical inflammation that may lead to a decrease in bone mineral density (BMD). The objective of this study was to assess BMD in Egyptian children with FMF on genetic basis.Methods: A cross sectional study included 45 FMF patients and 25 control children of both sexes in the age range between 3-16 years old. The patients were re...