chronic granulomatous disease (cgd) represents a group of inherited disorders of phagocytic system, manifesting recurrent infections at different sites. the present study was accomplished in order to determine the gastrointestinal manifestations of cgd patients. fifty-seven patients (38 males and 19 females) with cgd, who had been referred to three immunodeficiency referral centers in iran, wer...

there is a continuing need to identify new agents that are active in ovarian cancer. etoposide is a derivative of the plant alkaloid epipodophyllotoxin. the availability of etoposide in oral preparation allows prolonged administration by the oral route. in this study, activity and toxicity of etoposide in women with recurrent ovarian cancer are described from a case series of women with recurre...

Background: Evaluation of fat distribution is a way to assessment of physical health. Waist to Hip Ratio and waist circumference are the simplest anthropometric measurements to be used to determine the obesity and related disorders in pregnancy. Today a close consideration is given to WHR and WC assessment in order to evaluate physical health in epidemiological studies. Materials and Methods: O...

Background: The activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, Methods: All patients had plior platinum-based chemotherapy and developed progressive disease, Etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicit...

Introduction To define the clinical features, biochemical and histological findings and outcome of three forms of autoimmune hepatitis.   Materials and Methods In a cross sectional study between November 2001 to January 2008 in Tehran and Mashhad university of medical sciences, 61 children who diagnosed as AIH (40 girls and 21 boys) have been analyzed for their clinical, serological, and histol...

objective: the goal of this study is to evaluate the efficacy of intraperitoneal (jp) cisplatin as consolidation treatment, in epithelial ovarian cancer patients with pathologically negative surgical reassessment, following first-line platinum-based chemotherapy. methods: this study included 22 patients with figo stage (iic- iv) epithelial ovarian cancer (eoc) which had no evidence of disease a...

introduction: langerhans cell histiocytosis (lch) is a rare disease characterized by clonal prolifera-tion of histiocytosis in different tissues. permanent consequences (pc) described among subjects with langerhans cell histiocytosis (lch).in this study we report the prevalence of permanent sequel among long – term survivors of lch in our center. methods: we had 30 cases of lch from 1989 – 2001...