Accurate knowledge of the absolute North Atlantic Current (NAC) transport has been limited in the past by the di$culty of obtaining absolute velocity measurements. For this study, historical hydrography was combined with time series of round trip travel time from inverted echo sounders, bottom pressure sensor measurements, and measured velocities from deep current meters, via a `Gravest Empiric...

We have studied the binding of 102 ligands to the farnesoid X receptor within the D3R Grand Challenge 2016 blind-prediction competition. First, we employed docking with five different docking software and scoring functions. The selected docked poses gave an average root-mean-squared deviation of 4.2 Å. Consensus scoring gave decent results with a Kendall's τ of 0.26 ± 0.06 and a Spearman's ρ of...

69 ABSTRACT PURPOSE: To report the incidence of anisocoria after unilateral excimer laser photorefractive kera-tectomy (PRK) for myopia and subsequent cortico-steroid therapy in a retrospective and prospective study and to explore possible etiologies. METHODS: The horizontal pupil diameter was determined in 6 patients (6 eyes) at 21.8 ± 12.6 months after unilateral wide-field excimer laser PRK ...

A Markowitz-type portfolio selection problem is to minimize a deviation measure of portfolio rate of return subject to constraints on portfolio budget and on desired expected return. In this context, the inverse portfolio problem is finding a deviation measure by observing the optimal mean-deviation portfolio that an investor holds. Necessary and sufficient conditions for the existence of such ...