Estimators of the conditional expectation, i.e., prediction, function involve a global bias-variance trade off. In some cases, an estimator that yields unbiased estimates of the conditional expectation for a particular partitioning of the data may be desirable. Such estimators are calibrated with respect to the partitioning. We identify the conditional expectation given a particular partitionin...

We propose a class of transformation models for multivariate failure times. The class of transformation models generalize the usual gamma frailty model and yields a marginally linear transformation model for each failure time. Nonparametric maximum likelihood estimation is used for inference. The maximum likelihood estimators for the regression coefficients are shown to be consistent and asympt...

The most frequent measure of phylogenetic uncertainty for splits is bootstrap support. Although large bootstrap support intuitively suggests that a split in a tree is well supported, it has not been clear how large bootstrap support needs to be to conclude that there is significant evidence that a hypothesized split is present. Indeed, recent work has shown that bootstrap support is not first-o...

In this paper we investigate the large-sample behavior of the maximum likelihood estimate (MLE) of the unknown parameter θ for processes following the model dξt = θf(t)ξt dt+ dBt where f : R → R is a continuous function with period, say P > 0, and which is observed through continuous time interval [0, T ] as T → ∞. Here the periodic function f(·) is assumed known. We establish the consistency o...

the performance of many traffic control strategies depends on how much the traffic flow models are accurately calibrated. one of the most applicable traffic flow model in traffic control and management is lwr or metanet model. practically, key parameters in lwr model, including free flow speed and critical density, are parameterized using flow and speed measurements gathered by inductive loop d...

PURPOSE The purpose of this study was to evaluate sensitivity, specificity, and positive and negative likelihood ratios of laryngeal height, lung function, and diagnostic questionnaires for screening and diagnosis of chronic obstructive pulmonary disease (COPD). METHODS We undertook a cross-sectional study of 233 people aged between 40 and 75 years. Measured variables were age, sex, weight, h...