New WHO guidelines for measles outbreak response in measles mortality reduction settings now include reactive vaccination for outbreaks. Here we used surveillance data and vaccine coverage surveys following two mass vaccine campaigns in the Democratic Republic of Congo, to show the impact of reactive vaccination on reducing cases during outbreaks. The number of measles cases reported was collec...

universal vaccination of neonates and children against diphtheria, tetanus and pertussis has had a tremendous impact on the control of these infectious diseases worldwide. immunization by the triple diphtheria, tetanus and whole cell pertussis vaccine (dtwp) has been applied in iran for almost 50 years. periodic assessment of immunogenicity of this vaccine is an important aspect of successful m...

A cost-effectiveness analysis was made to determine the effectiveness of the following strategies of mass immunization with the new recombinant vaccine against the hepatitis B virus in Spain: vaccination of adolescents, newborns, both populations, and vaccination plus passive immunization of newborns of HBsAg positive mothers. Decision trees supported on Markov models with Monte Carlo simulatio...