In 2010 the US Food and Drug Administration (FDA) stated that it would issue guidance on its oversight of laboratory-developed tests (LDTs), and in July of that year the FDA held a public meeting to receive feedback on a risk-based application of LDT oversight (http:// www.fda.gov/MedicalDevices/NewsEvents/Workshops Conferences/ucm212830.htm). The FDA acknowledged that LDTs have been in existen...

In the half century since minimax was first suggested as a strategy for adversary game search, various search algorithms have been developed. The standard approach has been to use improvements to the Alpha-Beta (α-β) algorithm. Some of the more powerful improvements examine continuations beyond the nominal search depth if they are of special interest, while others terminate the search early. Th...

risk response planning is one of the main phases in the project risk management and has major impacts on the success of a large-scale project. since projects are unique, and risks are dynamic through the life of the projects, it is necessary to formulate responses of the important risks. the conventional approaches tend to be less effective in dealing with the impreciseness of risk response pl...

Risk management (RM) is today a commonly used term in many different disciplines (e.g. economy, industry, human resources, IT). Its goal is firstly to identify risks (e.g. of a machine operation, human behaviour or of a whole project) which can cause harm to properties, persons or environment. Secondly the RM should evaluate probabilities and severities of these unwanted events and propose meas...