Outpatient therapeutic programme (OTP) is one of the approaches community-based management acute malnutrition (CMAM), which includes community engagement and mobilization for outpatient uncomplicated severe (SAM) children 6–59 months with good appetite, by providing them home-based treatment as Ready-to-use Therapeutic Food (RUTF) routine medical treatment. Around 85-90% SAM are successfully tr...

OBJECTIVE Case death rates for severe childhood malnutrition remain stubbornly elevated in high HIV prevalence settings, despite the implementation of WHO guidelines. This study examined case death and other clinical outcomes in malnourished children with and without HIV infection. METHODS A prospective, observational study was undertaken at three tertiary hospitals in Johannesburg, South Afr...

BACKGROUND Although the risk factors for increased fatality among severely malnourished children have been reported, recent information from Africa, during a period of HIV pandemic and constrained health services, remains sketchy. The aim of this study has been to establish the risk factors for excess deaths among hospitalized severely malnourished children of below five years of age. METHOD ...

Serum and nasopharyngeal IgA antibody levels were estimated in 20 malnourished children and 20 matched healthy controls after immunization with a single dose of live attenuated measles or poliovirus vaccine. Seroconversion and serum neutralizing antibody titres were comparable in the two groups. Secretory IgA antibody was detected significantly less often in undernourished children; the time of...

BACKGROUND Subjective Global Assessment (SGA), a method of nutritional assessment based on clinical judgment, has been widely used to assess the nutritional status of adults for both clinical and research purposes. OBJECTIVE Foreseeing benefits of its use in children, we chose to adapt SGA and test its validity and reproducibility in the pediatric population. DESIGN We prospectively evaluat...

An inadequate and imbalanced intake of protein and energy results in protein-energy malnutrition (PEM). It is known that bone mineral density and serum magnesium levels are low in malnourished children. However, the roles of serum magnesium and endothelin-1 (ET-1) levels in the pathophysiology of bone mineralization are obscure. Thus, the relationships between serum magnesium and ET-1 levels an...

1. Basal levels of serum 25-hydroxy vitamin D (25-OHD) were estimated in ten normal children and twenty-seven children with protein-energy malnutrition. 2. Five normal children and fourteen malnourished children were administered a single massive dose of 15 mg vitamin D orally and the remaining children received oral supplements of 50 micrograms vitamin D daily for 20 d. Blood samples were obta...

The anthropometric measurements (height, weight and mid upper arm circumference) of children of working mothers in the age group of 12 to 60 months show a closeness in the values relating to urban and rural children although the males had higher values than females in all the age groups. The average Gomez percentage taking all the age groups combined were 91.59 and 86.95 in males against 95.54 ...

Antibodies to Herpesvirus hominis (HVH) types 1 and 2 were determined by a micro-neutralisation method in 37 children with kwashiorkor, 16 with marasmus, and in 64 well-nourished control children. All the children were aged between 1 and 4 years. The prevalence of antibodies was similar in the two sexes and at different ages. HVH-1 antibodies were present in 51% of children with kwashiorkor, in...