In the title compound, C(10)H(6)ClNO(2), the dihedral angle between the benzene and maleimide rings is 47.54 (9)°. Mol-ecules form centrosymmetric dimers through C-H⋯O hydrogen bonds, resulting in rings of graph-set motif R(2) (2)(8) and chains in the [100] direction. Mol-ecules are also linked by C-H⋯Cl hydrogen bonds along [001]. In this same direction, mol-ecules are connected to other neigh...

Porin from bovine heart mitochondria contains probably two cysteines (Cys126 and Cys230 in human porin, Kayser, H., Kratzin, H. D., Thinnes, F. P., Götz, H., Schmidt, W. E., Eckart, K. & Hilschmann, N. (1989) Biol. Chem. Hoppe-Seyler 370, 1265-1278). Reduced and oxidized forms of these cysteines were investigated in purified protein and in intact mitochondria using the agents dithioerythritol, ...

2010 This paper was presented in a preliminary draft version at the Thinktank session organised by IPEM, Ghent University, May 28 th 2010, held on the premises of the Logos Foundation.

BACKGROUND The laboratory diagnosis of hereditary spherocytosis commonly relies on NaCl-based or glycerol-based red cell osmotic fragility tests; more recently, an assay directly targeting the hereditary spherocytosis molecular defect (eosin-5'-maleimide-binding test) has been proposed. None of the available tests identifies all cases of hereditary spherocytosis. DESIGN AND METHODS We compare...

Functionalization of metal–organic frameworks (MOFs) is critical in exploring their structural and chemical diversity for numerous potential applications. Herein, we report multiple approaches the tandem postsynthetic modification (PSM) various MOFs derived from Zr(IV), Al(III), Zn(II). Our current work based on our efforts to develop a wide range MOF platforms with dynamic functional nature th...