The controls of food intake differ in male and female rats. Daily food intake is typically greater in male rats, relative to female rats, and a decrease in food intake, coincident with the estrous stage of the ovarian reproductive cycle, is well documented in female rats. This estrous-related decrease in food intake has been attributed to a transient increase in the female rat's sensitivity to ...

conclusions it seems that noise pollution has harmful effects on the fertility of males. also these findings may suggest the use of a natural curative approach rather than pharmaceutical drugs to optimize both neuroendocrine gonadal axis and testicular integrity induced by pathogenesis stress, and enhance fertility capacity in men. background this study was conducted to examine the efficacy of ...

A new spontaneously diabetic strain of the Sprague-Dawley rat was established in 1997 and named the SDT (Spontaneously Diabetic Torii) rat. In this research, we investigated the characteristics of the disease condition in the SDT rats. The time of onset of glucosuria was different between male and female SDT rats; glucosuria appeared at approximately 20 weeks of age in male rats and at approxim...

Hepatoprotective effect of gallic acid against type 2-induced diabetic liver injury in male rats through modulation fetuin-A and GLP-1 with involvement ERK1/2/NF-κB Wnt1/β-catenin signaling pathways

The present study was designed to examine sex differences in complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia and sex differences in opioid antinociception and anti-hyperalgesia. Female rats developed inflammation and hyperalgesia faster and exhibited greater peak hyperalgesia than male rats. In arthritic (CFA-treated) rats, lower thresholds were observed during estrus and proes...

Different parts of Icacina trichanta has been used for ethnomedicinal purposes; this study was undertaken to investigate the effects plant on CCl4- induced renal damage. Phytochemical analyses were carried out powdered sample using standard procedures. Absolute organ weight, Urea, creatinine, total protein, superoxide dismutase, catalase and malondialdehyde levels determined. Consequently, thir...

Background: Male infertility is considered a major cause of couple as it represents 25- 50 % cases. In addition, non-obstructive azoospermia (NOA) 10% all infertile men.There no definite curable treatment for such cases.
 Aim Work: The purpose this research was to assess the efficacy BM-MSCs and AT-MSCs in treating busulfan-induced wistar rats.
 Materials Methods: were extracted from ...

Aging is a critical risk factor for Parkinson's disease. Silibinin, a major flavonoid in Silybum marianum, has been suggested to display neuroprotective properties against various neurodegenerative diseases. In the present study, we observed that neonatal iron (120 μg/g body weight) supplementation resulted in significant abnormality of behavior and depletion of striatal dopamine (DA) in the ag...

The strain and sex differences in serum total cholesterol (TC) levels were examined in F344 and Sprague-Dawley (SD) rats. A sex difference (male<female) was observed in F344 rats but not in SD rats. The strain-dependent sex difference (male<female) was also observed in the constitutive gene expression level of hepatic 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGR), a rate-limiting enzyme for ...

Abstract Background and Aims Chronic kidney disease co-exists with heart failure preserved ejection fraction (HFpEF), which is characterized by the presence of obesity, hypertension, diabetes mellitus type 2. Obese ZSF1 rats, a model HFpEF, exhibit multiple these comorbidities that can disturb cardiac function. Little attention has been paid to how affect renal in rats. HFpEF found predominantl...