Introduction: Similarities in the memory impairment between Alzheimer patients and scopolamine treated animals have been reported. In the present study, the possible role of α-adrenergic receptors of the dorsal hippocampus on scopolamine state-dependent memory in adult male Wistar rats was evaluated. Methods: The animals were bilaterally implanted with chronic cannulae in the CA1 regions o...

Introduction: In this study, we investigated the role of N-Methyl-D-Aspartate (NMDA) receptors in the ventral hippocampus (VH) and their possible interactions with GABAA system on anxiety-like behaviors. Methods: We used an elevated-plus maze test (EPM) to assess anxiety-like behaviors and locomotor activity in male Wistar rats. Results: The results showed that intra-VH infusions of diffe...

Mean serum testosterone concentration in the 27-day-old prepubertal Holtzman rat was 0\m=.\25ng/ml, much lower than that observed in the adult male, 5\m=.\5ng/ml. Within 15 min after the intravenous injection of rat LH (in a dose of 400 ng-equiv. NIH-LH-S1/100 g body weight) serum testosterone concentration in the prepubertal rat increased approximately fivefold. Maximal elevation of serum test...

Diabetes Mellitus (DM) is an incurable disease that can be prevented clinically from worsening. This based on classification related to pancreatic damage in total or partial so the impact insulin production. Glucose transporter a protein glucose uptake outside cell into and provides important role body's homeostasis. transporter-2 (GLUT-2) found pancreas, liver, kidney. Parameters used are expr...

Objectives: The aim of this article is to explain the detailed methodology record Motor evoked potential (MEP) and somatosensory (SSEP) in adult albino Wistar rat, male (200–250 g) which has not been defined previously. Materials Methods: We have standardised recording both MEP SSEP these rats under anaesthesia on ADI digital polyrite system. Results: Evoked potentials widely studied spinal cor...

background: arsenic toxicity is a major global health problem and exposure via contaminated drinking water has been associated with hematological and other systemic disorders. the present investigation has been conducted in adult male rats to evaluate the protective ability of α-lipoic acid (ala) against such hematological disorders. methods: twenty-four adult male wister rats (b.wt.130±10g) we...