This study was designed to investigate the acute toxic effect of Diazinon on some blood parameters. Twelve male rabbits were divided randomly and equally into two groups, A treated group (T) control (C). Animals dipped in 3:1000 diazinon solution. Within 24 hours following treatment, animals showed moderate symptom organophosphorous poisoning such as dyspnia depression. Blood analysis revealed ...

Decline of growth hormone (GH) with aging is associated to memory and cognitive alterations. In this study, the number of neurons in the hilus of the dentate gyrus has been assessed in male and female Wistar rats at 3, 6, 12, 14, 18, 22 and 24 months of age, using the optical fractionator method. Male rats had more neurons than females at all the ages studied. Significant neuronal loss was obse...

Knot, Harm J., Karen M. Lounsbury, Joseph E. Brayden, and Mark T. Nelson. Gender differences in coronary artery diameter reflect changes in both endothelial Ca21 and ecNOS activity. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H961–H969, 1999.—Elevation of nitric oxide (NO) release from the vascular endothelium may contribute to some of the gender-associated differences in coronary artery fun...

Due to their strict maternal inheritance in most animals and plants, mitochondrial genomes are predicted to accumulate mutations that are beneficial or neutral in females but harmful in males. Although a few male-harming mtDNA mutations have been identified, consistent with this 'Mother's Curse', their effect on females has been largely unexplored. Here, we identify COII(G177S), a mtDNA hypomor...

Knot, Harm J., Karen M. Lounsbury, Joseph E. Brayden, and Mark T. Nelson. Gender differences in coronary artery diameter reflect changes in both endothelial Ca21 and ecNOS activity. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H961–H969, 1999.—Elevation of nitric oxide (NO) release from the vascular endothelium may contribute to some of the gender-associated differences in coronary artery fun...

Background Reproductive dysfunction and endocrine disorders are common among men with complex partial seizures of temporal lobe origin. Diminished sexual desire and responsiveness along with decreased libido and less orgasm are frequently described in men with temporal lobe epilepsy (TLE). It appears that the reduced fertility in epileptic men is accompanied by erectile dysfunction and abnormal...

in the present study, the effects of pregnant nmri mice restraint stress on the responsibility of their children to the behavioral properties of morphine, sulpiride and dextromethorphan were investigated in the f2 generation. twenty four pregnant nmri female mice (w: 25 g) were divided into the experimental and control groups (n = 12/group). animals in the experimental group were kept in the re...

Aggression in group-housed male mice is known to be influenced by both cage size and group size. However, the interdependency of these two parameters has not been studied yet. In this study, the level of aggression in groups of three, five, or eight male BALB/c mice housed in cages with a floor size of either 80 or 125 cm(2)/animal was estimated weekly after cage cleaning for a period of 14 wee...

The use of computer animation in behavioral research is a state-of-the-art method for designing and presenting animated animals to live test animals. The major advantages of computer animations are: (1) the creation of animated animal stimuli with high variability of morphology and even behavior; (2) animated stimuli provide highly standardized, controlled and repeatable testing procedures; and...

background and objective: tamoxifen is one of the selective estrogen receptor modulators that exerts estrogen / anti-estrogen effects in various tissues. this study was done to evaluate the effect of chronic administration of tamoxifen on spatial memory and passive avoidance task in adult male wistar rats. methods: in this experimental study, 48 adult male wistar rats were randomly divided into...