The influence of long-term alterations in dietary magnesium intake on blood pressure and on the antihypertensive effect of the calcium antagonist nifedipine was investigated in normotensive Wistar-Kyoto (WKY) and in spontaneously hypertensive rats (SHR). The rats were fed a diet either high (1%), normal (0.1%), or low (0.01%) in magnesium for 12 weeks (WKY) and 20 weeks (SHR), respectively. Nif...

In this study, ion exchange nanocomposite membranes was prepared by addition of Mg(OH)2 nanoparticles to a blend containing sulfonated polyphenylene oxide and sulfonated polyvinylchloride via a simple casting method. Magnesium hydroxide nanoparticles were synthesized via a facile sono-chemical reaction and were selected as filler additive in fabrication of ion exchange nanocomposite membranes. ...

Previously, we reported that the substrate shape recognition of the EScherichia coli ribonuclease (RNase) P ribozyme depends on the eoncentration of magnesium ion in vitro. We additional]y examined the Bacillvs subtilts RNase P ribozyme and found that the B. subti1ts enzyme also required high mag"esium ion, aboye 10 mM, for cleavage of a hairpin substrate. The results of kinetic studies showed ...

We describe an integrated automated system for the atomic absorption spectrophotometer. The system makes use of a light-dependent resistor to detect the presence of a marker ion which is present along with the sample ion in the flame. An electronic circuit has been developed which enables the marker ion to trigger the read signal of the spectrophotometer. The system has been tested by determini...

Magnesium is an essential ion that has an important role in regulating cell cycles and maintaining genomic stability (1). Administration of supplemental magnesium in animals with experimentally induced colon cancer resulted in fewer colon tumors and smaller cryptal cells of the colon (2), suggesting an inhibitory role of magnesium in colon cancer cell proliferation. The mechanism by which magne...

Magnesium is an essential ion that has an important role in regulating cell cycles and maintaining genomic stability (1). Administration of supplemental magnesium in animals with experimentally induced colon cancer resulted in fewer colon tumors and smaller cryptal cells of the colon (2), suggesting an inhibitory role of magnesium in colon cancer cell proliferation. The mechanism by which magne...

BACKGROUND Magnesium ion is critical for life and is integrally involved in cellular function and a key component of normal bone mineral. In health, the kidneys, gastrointestinal tract and bone are responsible for maintaining serum magnesium concentrations in the normal range and magnesium balance. Most clinical disorders involving magnesium, other than chronic kidney disease (CKD), result in h...

In the United States the literature contains only sporadic references to clinical disorders of Mg-deficiency, compared to more recent interest in the benefits of magnesium infusion in myocardial infarction and other acute clinical conditions [1,2]. In Europe the clinical interest in Mg-deficiency was pioneered by Durlach in his book entitled Le Magnesium en Prutique Clinique; the English editio...

Traumatic brain injury results in a profound decline in intracellular magnesium ion levels that may jeopardize critical cellular functions. We examined the consequences of preinjury magnesium deficiency and post-traumatic magnesium treatment on injury-induced cytoskeletal damage and cell death at 24 h after injury. Adult male rats were fed either a normal (n = 24) or magnesium-deficient diet (n...

Nonaqueous rechargeable magnesium (Mg) batteries suffer from the complicated and moisture-sensitive electrolyte chemistry. Besides electrolytes, the practicality of a Mg battery is also confined by the absence of high-performance electrode materials due to the intrinsically slow Mg2+ diffusion in the solids. In this work, we demonstrated a rechargeable aqueous magnesium ion battery (AMIB) conce...