Centriolar satellites (CS) are small granular structures that cluster in the vicinity of centrosomes. CS are highly susceptible to stress stimuli, triggering abrupt displacement of key CS factors. Here we discover a linear p38-MK2-14-3-3 signalling pathway that specifically targets CEP131 to trigger CS remodelling after cell stress. We identify CEP131 as a substrate of the p38 effector kinase M...

Abstract The eight digester towers at New York City's Newtown Creek Wastewater Treatment Plant seamlessly convert sewage into biogas and a dirt-like output, similar to how Mother Nature would do it. At 145 feet high 80 in diameter, each egg holds about 3 million gallons of sludge, converting it 2 cubic gas every day.

THIS little book by Professor Rendle Short sets out to give an account of the structure and functions of the human body for the non-medical reader, and to present the student of physiology with accurate and up-to-date facts from a somewhat unusual angle. There is no doubt that the author succeeds in both these objects, and he gives a most interesting and instructive set of chapters ranging in s...

The latest fad in Continental philosophy is an unexpected one. Goodbye to Lacan and Derrida and even Deleuze. Hello to the Apostle Paul. Atheist philosophers like Alain Badiou and Slavoj Zizek have coopted Paul to their own agendas, and in their wake Jewish thinkers like Jacob Taubes and radically orthodox Christian theologians (the usual suspects) have given fresh attention to the apostle. Of ...

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polycrystalline mfi zeolite membranes were prepared on α-alumina tubular support by hydrothermal treatments at 413 k. the synthesized zeolite membranes were characterized by xrd, sem and single gas permeation. the influence of hydrothermal treatment steps and the calcination time on the zeolite layer formation were investigated. mfi zeolite membrane prepared by four subsequent hydrothermal trea...

 Gastrointestinal disorders: abdominal discomfort, abdominal pain, constipation, diarrhea, dyspepsia, nausea, vomiting.  General disorders and administration site conditions: malaise, peripheral edema, pyrexia.  Immune System Disorders: Drug hypersensitivity to include facial edema, urticaria, angioedema and laryngeal edema.  Musculoskeletal and connective tissue disorders: myalgia  Nervou...