Diabetes during pregnancy results in congenital malformations and long-term postnatal diseases. Experimental models are still needed to investigate the mechanism responsible for these alterations. Thus, by the administration of different doses of streptozotocin (STZ) (0, 25, 30, or 35 mg/kg body weight, intravenous) at the onset of pregnancy in rats, the present study sought an appropriate anim...

The objectives of this study were to estimate the burden of diabetes and to explore the adverse pregnancy outcomes associated with pregestational diabetes mellitus (pre-GDM) and gestational diabetes mellitus (GDM) among the Saudi pregnant population. In this subcohort, we compared the maternal and the neonatal outcomes of diabetic women with pre-GDM and GDM to the outcomes of nondiabetic mother...

Abstract Background and purpose: Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnancy. It was known one of the complications of this period. The aim of this study was to investigate the relationship between some risk factors with GDM in pregnant women in Zahedan, Iran. Materials and Methods: In a descriptive-analytical study, 70 pregnant women with GDM and 140 ...