A case of probable vertical transmission of Mycoplasma pneumoniae is presented. The presence of M pneumoniae was demonstrated by the polymerase chain reaction (PCR) in the nasopharyngeal aspirate of a newborn who developed pneumonia shortly after birth. This result was confirmed by performing a second PCR, amplifying another part of the genome of M pneumoniae. It is concluded that M pneumoniae ...

An important role in the treatment regimens for Mycoplasma pneumoniae infections is played by macrolide (ML) antibiotics. In the past few years, however, a steady increase has been detected in the worldwide prevalence of ML-resistant (ML(r)) M. pneumoniae strains. It is obvious that this increase necessitates a continuous monitoring of ML(r) and, when detected, modification of antibiotic treatm...

M. pneumoniae respiratory infection is usually mild and self-limiting. We report a case of acute respiratory distress syndrome (ARDS) due to M. pneumoniae infection in a 60 years old woman. Quick diagnosis was established by multiplex PCR assay for detection of pneumonia-causing bacteria. Outcome was favorable. The factors accounting for the severity of pneumonia caused by M. pneumoniae are dis...

BACKGROUND Previous studies investigating the relationship between Mycoplasma pneumoniae and incident asthma in the general population have been inconclusive. OBJECTIVE We conducted a nationwide cohort study to clarify this relationship. METHODS Using the National Health Insurance Research Database of Taiwan, we identified 1591 patients with M pneumoniae infection (International Classificat...

Mycoplasma pneumoniae is one of the most common causes of respiratory infections in children and adults worldwide [1,2]. This bacterial pathogen is estimated to be responsible for at least one case of pneumonia per 1,000 persons and .100,000 adult hospitalizations per year in the United States alone [1–3]. The infection is mostly mild, but all age groups can experience more severe disease, and ...

BACKGROUND M. pneumoniae is a common cause of respiratory tract infections (RTIs) of variable severity especially in children. New diagnostic techniques offered more reliable information about the epidemiology of infection by this pathogen. AIM The aim of this study was to investigate the prevalence and epidemiology of acute M. pneumoniae infections among Greek children hospitalized for RTIs ...

BACKGROUND AND OBJECTIVE Children with community-acquired lower respiratory tract infection (CA-LRTI) commonly receive antibiotics for Mycoplasma pneumoniae. The objective was to evaluate the effect of treating M. pneumoniae in children with CA-LRTI. METHODS PubMed, Cochrane Central Register of Controlled Trials, and bibliography review. A search was conducted by using Medical Subject Heading...

Interferon (IFN) production by human peripheral lymphocytes stimulated with M. pneumoniae was investigated. The hydrogen peroxide released from M. pneumoniae was responsible for the induction of IFN from lymphocytes, since horseradish peroxidase inhibited the IFN production and abrogated the activity of IFN production in the supernatant of M. pneumoniae. The antiserum neutralizing IFN alpha and...

both c. pneumoniae and m. pneumoniae are common causes of respiratory tract infection. at present, both are still diagnosed in the laboratory retrospectively by serology. this is despite many publications which indicate that pcr, which is not retrospective, is extremely good at detecting these organisms. we thought that a single pcr test which could detect both organisms simultaneously in a rou...

A serological study was undertaken to investigate infections in active-duty United States soldiers with illnesses characterized by prolonged, afebrile, nonproductive coughs. Fifty-four soldiers were enrolled with such illness of >/=2 weeks' duration (case patients) along with 55 well soldiers (control subjects). Serum samples were tested for IgG and IgA antibody to 3 Bordetella pertussis antige...