Using a dispersed human luteal cell culture model, progesterone synthesis following treatment by incremental doses of human chorionic gonadotrophin (HCG) and the stable prostaglandin F2alpha (PGF2alpha) analogue cloprostenol, alone or in combination, was related to corpora lutea (CL) mRNA transcript abundance coding for the luteinizing hormone (LH)/HCG receptor (LH-R) and PGF2alpha-receptor (FP...

introduction: the implantation is a complex procedure that involves many molecules. one of these molecules is integrin specially &alphav;&beta3; which serves as receptor for components of extra cellular matrix to act as bridging molecules between the blastocyst and the endometrial surface during the implantation process. by blocking &alphav;&beta3; interactions, the implantation can be impaired...

objective: several studies have shown the improving effect of heparin on the outcomes of art. moreover, it has been reported that adding heparin in non-thrombophilia patients with rif is useful.the aim of this study was to evaluate the beneficial effects of heparin on art outcomes in women with history of recurrent implantation failure (rif) and without history of congenital or acquired thrombo...

To investigate the possible role of the superoxide radical and its scavenging system in the human corpus luteum, superoxide dismutase (SOD) values and lipid peroxide concentrations were analysed in the corpora lutea during the menstrual cycle and in early pregnancy. Copper-zinc SOD (Cu,Zn-SOD) activities increased from the early to mid-luteal phase, and gradually decreased thereafter and were t...

Regression of the corpus luteum (CL) is characterized by a decay in progesterone (P4) production (functional luteolysis) and disappearance of luteal tissues (structural luteolysis). In mares, structural luteolysis is thought to be caused by apoptosis of luteal cells, but functional luteolysis is poorly understood. 20α-hydroxysteroid dehydrogenase (20α-HSD) catabolizes P4 into its biologically i...

PURPOSE To identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the nonmalignant fallopian tube epithelium (FTE) of BRCA1/2 mutation carriers, given recent evidence implicating the distal FTE as a common source for SerCa. EXPERIMENTAL DESIGN We obtained and compared gene expression profiles of laser capture microdissected nonmalignant di...

BACKGROUND Menstrual cycle-related symptoms are an important health issue for many women, and some may affect cardiac autonomic regulation. In the present study, we evaluated the cardiovascular and physiological stress response to 12-h short-term fasting in the menstrual phases of healthy young women. METHODS We performed a randomized crossover study. Subjects were seven female university stu...

an experiment was conducted to investigate the effect of different types of ovarian cycles on reproductive indices and blood metabolites in 61 holstein cows. blood samples were taken from each cow between day 12 and day 50 postpartum (pp). serum progesterone concentrations were measured to determine the onset of luteal function and different types of luteal dysfunctions in cows. serum glucose, ...

OBJECTIVE To compare the efficacy of intravaginal and IMP for luteal phase support in IVF cycles. DESIGN Prospective trial. SETTING Tertiary care private practice. PATIENT(S) Women 25-44 years old with infertility necessitating treatment with IVF. From April 1, 2008-April 1, 2009, 511 consecutive patients were enrolled; 474 completed participation, and 37 were excluded for no autologous E...