common lupus. BMJ 1888; 1:58–63 3 Su WP, Perniciaro C, Rogers RS III, et al. Chilblain lupus erythematosus (lupus pernio): clinical review of the Mayo Clinic experience and proposal of diagnostic criteria. Cutis 1994; 54:395–399 4 Hedrich CM, Fiebig B, Hauck FH, et al. Chilblain lupus erythematosus: a review of literature. Clin Rheumatol 2008; 27:1341 5 Richez C, Dumoulin C, Schaeverbeke T. Inf...

Lupus erythematosus profundus, a form of chronic cutaneous lupus erythematosus, is a rare inflammatory disease involving in the lower dermis and subcutaneous tissues. It primarily affects the head, proximal upper arms, trunk, thighs, and presents as firm nodules, 1 to 3 cm in diameter. The overlying skin often becomes attached to the subcutaneous nodules and is drawn inward to produce deep, sau...

matosus. A similar case of Sjogren syndrome and subsequent development of systemic lupus erythematosus has been reported in a 12 year old boy.3 In our patient, two points remain to be clarified, whether the seizures were the first symptom of systemic lupus erythematosus central nervous system involvement and whether any relation can be found between the phenobarbitone treatment and the onset of...

Blood rheology is one of the determinants of perfusion and might therefore have an impact on the thromboembolic complications of lupus erythematosus. This study aimed at defining the flow properties of blood in patients with various types of lupus erythematosus. Results for 51 patients were compared with those for 20 controls matched for sex. The patients were divided into subgroups--chronic di...

1. Nelson WE, Vaughan III, VC, McKay, Jr., RJ and Behrman RE, editors. Textbook of pediatrics, Philadelphia, 1979, W B Saunders Company. 2. Rudolph AM, Barnett HL, and Einhorn AH, editors: Pediatrics, ed 16, New York, 1977, Appleton-CenturyCrofts. 3. Irgang S: Lupus erythematosus profundus. Report of an example with clinical resemblance to Darier-Roussy sarcoid, Arch Dermatol 42:97, 1940. 4. Fo...

BACKGROUND Thyroid autoimmunity is considered the most common type of organ-specific autoimmune disorder and can be associated with other autoimmune endocrine disorders or non-endocrine diseases. Systemic lupus erythematosus is a prototypical autoimmune disorder with multifactorial etiology. The pathogenesis and development of the disease may result from a loss of immune tolerance and the resul...

BACKGROUND AND PURPOSE Multiple sclerosis and neuropsychiatric systemic lupus erythematosus are autoimmune diseases with similar CNS inflammatory and neurodegenerative characteristics. Our aim was to investigate white matter tract changes and their association with cognitive function in patients with MS and those with neuropsychiatric systemic lupus erythematosus compared with healthy controls ...

The lupus erythematosus cell (L.E. cell) phenomenon is usually regarded, if properly interpreted, as being almost specific for systemic lupus erythematosus (Wilkinson and Sacker, 1957). On the other hand, too rigid an outlook may lead to diagnostic errors or retard progress in the understanding of other diseases. Careful repeated examination of the blood of patients with classical rheumatoid ar...

Systemic lupus erythematosus is a group of diseases that seem to become separate entities by etiology in the near future. Its pathogenesis remains elusive; however, multifactorial interactions among genetic and environmental factors may be involved. Systemic lupus erythematosus is the perfect prototype of autoimmune disorder with multiple derangements, starting from innate immunity to adaptive ...

Angioedema secondary to C1 inhibitor deficiency has been rarely reported to be associated with systemic lupus erythematosus. A genetic defect of C1 inhibitor produces hereditary angioedema, which is usually presented with cutaneous painless edema, but edema of the genital area, gastrointestinal and laryngeal tracts have also been reported.In lupus patients, angioedema may be the result of an ac...